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Open Access

A surgeon's guide to anticoagulant and antiplatelet medications part one: warfarin and new direct oral anticoagulant medications

Paul B McBeth, Jordan A Weinberg, Babak Sarani, Louise Y Y Yeung, Addison K May
DOI: 10.1136/tsaco-2016-000020 Published 13 July 2016
Paul B McBeth
1Departments of Surgery and Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada
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Jordan A Weinberg
2Department of Surgery, Dignity Health/St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA
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Babak Sarani
3Center for Trauma and Critical Care, George Washington University, Washington DC, USA
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Louise Y Y Yeung
4Kaiser Permanente, Los Angeles, California, USA
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Addison K May
5Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
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Abstract

An increasing number of potent antiplatelet and anticoagulant medications are being used for the long-term management of cardiac, cerebrovascular, and peripheral vascular conditions. Management of these medications in the perioperative and peri-injury settings can be challenging for surgeons, mandating an understanding of these agents and the risks and benefits of various management strategies. In this two-part review, agents commonly encounter by surgeons in the perioperative and peri-injury settings are discussed and management strategies for patients on long-term antiplatelet and anticoagulant therapy reviewed. In part I, we review warfarin and the new direct oral anticoagulants. In part II, we review antiplatelet agents and assessment of platelet function and the perioperative management of long-term anticoagulant and antiplatelet therapy.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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A surgeon's guide to anticoagulant and antiplatelet medications part one: warfarin and new direct oral anticoagulant medications
Paul B McBeth, Jordan A Weinberg, Babak Sarani, Louise Y Y Yeung, Addison K May
Trauma Surg Acute Care Open Jul 2016, 1 (1) e000020; DOI: 10.1136/tsaco-2016-000020

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A surgeon's guide to anticoagulant and antiplatelet medications part one: warfarin and new direct oral anticoagulant medications
Paul B McBeth, Jordan A Weinberg, Babak Sarani, Louise Y Y Yeung, Addison K May
Trauma Surg Acute Care Open Jul 2016, 1 (1) e000020; DOI: 10.1136/tsaco-2016-000020
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A surgeon's guide to anticoagulant and antiplatelet medications part one: warfarin and new direct oral anticoagulant medications
Paul B McBeth, Jordan A Weinberg, Babak Sarani, Louise Y Y Yeung, Addison K May
Trauma Surgery & Acute Care Open Jul 2016, 1 (1) e000020; DOI: 10.1136/tsaco-2016-000020
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