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Open Access

Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial

Thomas J Schroeppel, John P Sharpe, Charles Patrick Shahan, Lesley P Clement, Louis J. Magnotti, Marilyn Lee, Michael Muhlbauer, Jordan A Weinberg, Elizabeth A Tolley, Martin A Croce, Timothy C Fabian
DOI: 10.1136/tsaco-2019-000307 Published 18 August 2019
Thomas J Schroeppel
1Department of Acute Care Surgery, UCHealth Memorial Hospital Central, Colorado Springs, Colorado, USA
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John P Sharpe
2Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
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Charles Patrick Shahan
2Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
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Lesley P Clement
3Department of Pharmacy, UCHealth Memorial Hospital Central, Colorado Springs, Colorado, USA
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Louis J. Magnotti
2Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
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Marilyn Lee
4Department of Pharmacy, Regional One Health, Memphis, Tennessee, USA
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Michael Muhlbauer
5Department of Neurosurgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
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Jordan A Weinberg
6Department of Surgery, Dignity Health Medical Group Arizona, Phoenix, Arizona, USA
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Elizabeth A Tolley
7Department of Preventative Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA
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Martin A Croce
2Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
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Timothy C Fabian
2Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
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Article Information

vol. 4 no. 1
DOI 
https://doi.org/10.1136/tsaco-2019-000307

Online ISSN 
2397-5776
History 
  • Received February 26, 2019
  • Revised June 24, 2019
  • Accepted July 5, 2019
  • Published online August 18, 2019.

Copyright & Usage 
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Thomas J Schroeppel1,
  2. John P Sharpe2,
  3. Charles Patrick Shahan2,
  4. Lesley P Clement3,
  5. Louis J. Magnotti2,
  6. Marilyn Lee4,
  7. Michael Muhlbauer5,
  8. Jordan A Weinberg6,
  9. Elizabeth A Tolley7,
  10. Martin A Croce2,
  11. Timothy C Fabian2
  1. 1Department of Acute Care Surgery, UCHealth Memorial Hospital Central, Colorado Springs, Colorado, USA
  2. 2Department of Surgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
  3. 3Department of Pharmacy, UCHealth Memorial Hospital Central, Colorado Springs, Colorado, USA
  4. 4Department of Pharmacy, Regional One Health, Memphis, Tennessee, USA
  5. 5Department of Neurosurgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA
  6. 6Department of Surgery, Dignity Health Medical Group Arizona, Phoenix, Arizona, USA
  7. 7Department of Preventative Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA
  1. Correspondence to Dr Thomas J Schroeppel, Department of Acute Care Surgery, UCHealth Memorial Hospital Central, Colorado Springs, CO 80909, USA; thomas.schroeppel{at}uchealth.org
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Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial
Thomas J Schroeppel, John P Sharpe, Charles Patrick Shahan, Lesley P Clement, Louis J. Magnotti, Marilyn Lee, Michael Muhlbauer, Jordan A Weinberg, Elizabeth A Tolley, Martin A Croce, Timothy C Fabian
Trauma Surg Acute Care Open Aug 2019, 4 (1) e000307; DOI: 10.1136/tsaco-2019-000307

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Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial
Thomas J Schroeppel, John P Sharpe, Charles Patrick Shahan, Lesley P Clement, Louis J. Magnotti, Marilyn Lee, Michael Muhlbauer, Jordan A Weinberg, Elizabeth A Tolley, Martin A Croce, Timothy C Fabian
Trauma Surg Acute Care Open Aug 2019, 4 (1) e000307; DOI: 10.1136/tsaco-2019-000307
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Beta-adrenergic blockade for attenuation of catecholamine surge after traumatic brain injury: a randomized pilot trial
Thomas J Schroeppel, John P Sharpe, Charles Patrick Shahan, Lesley P Clement, Louis J. Magnotti, Marilyn Lee, Michael Muhlbauer, Jordan A Weinberg, Elizabeth A Tolley, Martin A Croce, Timothy C Fabian
Trauma Surgery & Acute Care Open Aug 2019, 4 (1) e000307; DOI: 10.1136/tsaco-2019-000307
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