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Open Access

Intraoperative REBOA: an analysis of the American Association for the Surgery of Trauma AORTA registry

Michael A Vella, Ryan Peter Dumas, Joseph DuBose, Jonathan Morrison, Thomas Scalea, Laura Moore, Jeanette Podbielski, Kenji Inaba, Alice Piccinini, David S Kauvar, Valorie L Baggenstoss, Chance Spalding, Charles Fox, Ernest E Moore, Jeremy W Cannon
DOI: 10.1136/tsaco-2019-000340 Published 11 November 2019
Michael A Vella
1Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
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Ryan Peter Dumas
1Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
2Division of General and Acute Care Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Joseph DuBose
3R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland, USA
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Jonathan Morrison
3R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland, USA
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  • ORCID record for Jonathan Morrison
Thomas Scalea
3R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland, USA
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Laura Moore
4Division of Trauma and Surgical Critical Care, University of Texas, Houston, Texas, USA
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Jeanette Podbielski
4Division of Trauma and Surgical Critical Care, University of Texas, Houston, Texas, USA
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Kenji Inaba
5Division of Surgical Critical Care and Trauma, Los Angeles County + University of Southern California Hospital, Los Angeles, California, USA
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Alice Piccinini
5Division of Surgical Critical Care and Trauma, Los Angeles County + University of Southern California Hospital, Los Angeles, California, USA
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David S Kauvar
6Division of Trauma and Surgical Critical Care, San Antonio Military Medical Center/US Army Institute of Surgical Research, San Antonio, Texas, USA
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Valorie L Baggenstoss
6Division of Trauma and Surgical Critical Care, San Antonio Military Medical Center/US Army Institute of Surgical Research, San Antonio, Texas, USA
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Chance Spalding
7Department of Surgery, Grant Medical Center, Columbus, Ohio, USA
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Charles Fox
8Department of Surgery, Denver Health Medical Center, Denver, Colorado, USA
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Ernest E Moore
8Department of Surgery, Denver Health Medical Center, Denver, Colorado, USA
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Jeremy W Cannon
1Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
9Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
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Article Figures & Data

Tables

  • Supplementary Materials
  • Table 1

    Characteristics of patients undergoing OR vs. ED REBOA placement

    TotalOR REBOAED REBOAP value
    (n=305)(n=58)(n=247)
    Age39 (26–57)32.5 (22–51)40.5 (27–58)0.01
    Sex 0.92
     Male233 (76.4)44 (75.8)189 (76.5)
     Female72 (23.6)14 (24.2)58 (23.5)
    Mechanism <0.001
     Penetrating59 (19.3)21 (36.3)38 (15.4)
     Blunt243 (79.6)37 (63.7)206 (83.4)
    ISS 34 (25–42)34 (25–45)0.38
    Admission SBP82 (49–114)110 (80–130)80 (0–111)<0.001
    Admission HR106 (69–130)114 (92–132)101 (52–129)0.04
    Admission GCS score3 (3–13)7 (3–15)3 (3–9)<0.001
    Admission lactate8.2 (5–11.8)6.5 (3.9–10.8)8.2 (5.2–12.1)0.05
    Prehospital CPR89 (29.1)2 (3.4)87 (35.2)<0.001
    Time from admission to AO (min)25 (15–46)75 (36–110)23 (14–27)<0.001
    Time to definitive hemorrhage control91 (53–165)116 (78–172)79 (48–155)0.01
    Occlusion time (min)32 (12.5–66)33 (11–67)30 (15–63)0.61
    pRBC (units)12 (6–25)16 (8–28)12 (5–22)0.06
    Acute kidney injury57 (18.7)10 (17.2)47 (19.0)0.75
    Mortality191 (62.6)21 (36.2)170 (68.8)<0.001
    • Data for non-parametric continuous variables expressed as median (IQR); categorical values expressed as n (%).

    • AO, aortic occlusion;CPR, cardiopulmonary resuscitation; ED, emergency department; GCS, Glasgow Coma Scale; HR, heart rate; ISS, Injury Severity Score;OR, operating room; pRBC, packed red blood cells; REBOA, resuscitative endovascular balloon occlusion of the aorta; SBP, systolic blood pressure.

  • Table 2

    Univariate analysis on the outcome of in-hospital mortality

    OR95% CIP value
    Admission time to successful AO0.980.981 to 0.9960.002
    Admission GCS score0.780.743 to 0.834<0.001
    Admission HR0.980.984 to 0.995<0.001
    Admission SBP0.980.984 to 0.995<0.001
    ISS1.021.006 to 1.0450.009
    Age1.021.004 to 1.0330.013
    Admission lactate1.11.034 to 1.1750.003
    CPR9.34.064 to 21.189<0.001
    Location of AO (operating room)0.530.393 to 0.737<0.001
    • AO, aortic occlusion; CPR, cardiopulmonary resuscitation; GCS, Glasgow Coma Scale; HR, heart rate; ISS, Injury Severity Score; SBP, systolic blood pressure.

  • Table 3

    Multivariate logistic regression analysis on the outcome of in-hospital mortality

    OR95% CIP value
    Admission time to successful AO1.000.981 to 1.0210.921
    Admission GCS score0.800.720 to 0.900<0.001
    Admission HR1.010.996 to 1.0280.158
    Admission SBP0.990.980 to 1.0120.627
    ISS1.051.006 to 1.0900.025
    Age1.061.021 to 1.1010.002
    Admission lactate1.080.978 to 1.2080.123
    CPR10.161.440 to 71.7450.02
    Location of AO (operating room)1.80.295 to 11.4980.513
    • Number of observations: 106.

    • AO, aortic occlusion; CPR, cardiopulmonary resuscitation; GCS, Glasgow Coma Scale; HR, heart rate; ISS, Injury Severity Score; SBP, systolic blood pressure.

Supplementary Materials

  • Tables
  • Supplementary data

    [tsaco-2019-000340supp001.pdf]

  • Supplementary data

    [tsaco-2019-000340supp002.pdf]

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Intraoperative REBOA: an analysis of the American Association for the Surgery of Trauma AORTA registry
Michael A Vella, Ryan Peter Dumas, Joseph DuBose, Jonathan Morrison, Thomas Scalea, Laura Moore, Jeanette Podbielski, Kenji Inaba, Alice Piccinini, David S Kauvar, Valorie L Baggenstoss, Chance Spalding, Charles Fox, Ernest E Moore, Jeremy W Cannon
Trauma Surg Acute Care Open Nov 2019, 4 (1) e000340; DOI: 10.1136/tsaco-2019-000340

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Intraoperative REBOA: an analysis of the American Association for the Surgery of Trauma AORTA registry
Michael A Vella, Ryan Peter Dumas, Joseph DuBose, Jonathan Morrison, Thomas Scalea, Laura Moore, Jeanette Podbielski, Kenji Inaba, Alice Piccinini, David S Kauvar, Valorie L Baggenstoss, Chance Spalding, Charles Fox, Ernest E Moore, Jeremy W Cannon
Trauma Surg Acute Care Open Nov 2019, 4 (1) e000340; DOI: 10.1136/tsaco-2019-000340
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Intraoperative REBOA: an analysis of the American Association for the Surgery of Trauma AORTA registry
Michael A Vella, Ryan Peter Dumas, Joseph DuBose, Jonathan Morrison, Thomas Scalea, Laura Moore, Jeanette Podbielski, Kenji Inaba, Alice Piccinini, David S Kauvar, Valorie L Baggenstoss, Chance Spalding, Charles Fox, Ernest E Moore, Jeremy W Cannon
Trauma Surgery & Acute Care Open Nov 2019, 4 (1) e000340; DOI: 10.1136/tsaco-2019-000340
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