Figure 1 Timeline and vitals. (A) Schematic depicting experimental timeline, with time points running from instrumentation, through hemorrhage, prolonged field care, hospital care, postoperative observation and euthanasia. Blood draws were obtained at each indicated time point for labs (arterial blood gas and serum chemistries) at baseline (BSLN), end of shock (EOS), prolonged field care (PFC1), PFC2, PFC4, END PFC, end of hospital care (EHC) and euthanasia (Final). Vitals were continuously monitored throughout the operational stages of the protocol. Data are presented as mean±SD for (B) mean arterial pressure (MAP), (C) systolic blood pressure (SBP), and (D) heart rate. Lines indicate groups: group 1 (NS/NT, n=5, solid line); group 2 (NS/PH, n=5, dashed line); group 3 (Decomp/PH, n=5, dashed/dotted line). P values <0.05 were considered to be statistically significant. Significant differences between groups are indicated as: *NS/NT versus NS/PH, †NS/NT versus Decomp/PH, #NS/PH versus Decomp/PH, $NS/NT versus BSLN, ‡NS/PH versus BSLN, &Decomp/PH versus BSLN. BPM, beats per minute; END PFC, end of prolonged field care; HR, heart rate; NS, non-shock; NT, normotensive; PH, permissive hypotension