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Open Access

Revision of ‘golden hour’ for hemodynamically unstable trauma patients: an analysis of nationwide hospital-based registry in Japan

Kazuhiro Okada, Hisashi Matsumoto, Nobuyuki Saito, Takanori Yagi, Mihye Lee
DOI: 10.1136/tsaco-2019-000405 Published 10 March 2020
Kazuhiro Okada
1Shock and Trauma Center, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan
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Hisashi Matsumoto
1Shock and Trauma Center, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan
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Nobuyuki Saito
1Shock and Trauma Center, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan
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Takanori Yagi
1Shock and Trauma Center, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan
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Mihye Lee
2School of Public Health, St Luke's International University, Tokyo, Japan
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    Figure 1

    Distribution of time from injury to definitive care.

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    Figure 2

    Non-parametric curves of trend in log odds of in-hospital mortality with time to definitive care using the generalized additive model for total patients (n=1169). The shade bands showed 95% CI.

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    Figure 3

    Non-parametric curves of trend in log odds of in-hospital mortality with time to definitive care using generalized additive models ((A) severe shock patients: n=777; (B) moderate shock patients: n=392). The shade bands showed 95% CI.

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    Figure 4

    Non-parametric curves of trend in log odds of in-hospital mortality with time from actual time from injury onset to definitive care using the generalized additive model (n=798). The shade bands showed 95% CI.

Tables

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  • Table 1

    Characteristics of patients

    TotalSevere shockModerate shock
    n=1169n=777n=392
    Median age, year (IQR)50.0(34.0–67.0)54.0(36.0–70.0)43.5(30.0–60.0)
    Male (%)779(66.6)513(66.0)266(67.9)
    Year of occurrence
     2006–2010 (%)478(40.9)306(39.4)392(43.9)
     2011–2015 (%)691(59.1)471(60.6)220(56.1)
    Penetrating injury (%)271(23.2)169(21.8)102(26.0)
    Transport measure (%)
    Ambulance975(83.4)649(83.5)326(83.2)
    Doctor-staffed car82(7.0)57(7.3)25(6.4)
    Helicopter112(9.6)71(9.1)41(10.5)
    Median ISS (IQR)29.0(16.0–41.0)27.0(16.0–41.0)29.0(16.0–41.0)
    Median AIS (IQR)
     Brain0.0(0.0–3.0)0.0(0.0–3.0)0.0(0.0–3.0)
     Chest3.0(0.0–4.0)2.0(0.0–4.0)3.0(0.0–4.0)
     Abdomen2.0(0.0–3.0)2.0(0.0–4.0)2.0(0.0–3.0)
     Lower extremities and pelvis2.0(0.0–4.0)2.0(0.0–4.0)1.0(0.0–4.0)
    Vital signs on arrival, median (IQR)
     SBP62.0(40.0–74.0)54.0(40.0–62.0)80.0(74.0–84.0)
     RR25.0(20.0–30.0)24.0(20.0–30.0)26.0(20.0–32.0)
     HR119.0(93.0–133.0)107.0(82.0–127.0)126.0(118.0–140.0)
     GCS12.0(6.0–14.0)12.0(6.0–14.0)13.0(7.0–14.0)
    Type of procedure in ED (%)
     Intubation770(65.9)524(67.4)246(62.8)
     ERT69(5.9)51(6.6)18(4.6)
     REBOA154(13.2)120(15.4)34(8.7)
     Transfusion948(81.1)626(80.6)322(82.1)
    Type of definitive care (%)
     Craniotomy50(4.3)33(4.2)17(4.3)
     Thoracotomy159(13.6)105(13.5)54(13.8)
     Laparotomy387(33.1)256(32.9)131(33.4)
     Orthopedic surgery141(12.1)99(12.7)42(10.7)
     TAE340(29.1)226(29.1)114(29.1)
    Median time interval, min (IQR)
     From injury to arrival at hospital37.0(28.0–48.0)36.0(28.0–48.0)37.0(28.0–49.0)
     From arrival at hospital to definitive care95.0(61.0–133.0)93.0(60.0–132.0)100.0(63.0–137.0)
     From injury to definitive care137.0(102.0–177.0)136.0(101.0–177.0)139.0(103.8–179.2)
    Hospital course
     In-hospital mortality386(33.0)282(36.3)104(26.5)
     Median length of stay in hospital (IQR)20.0(2.0–58.8)17.0(1.0–59.0)24.0(4.0–58.0)
    • AIS, Abbreviated Injury Scale; ED, emergency department; ERT, emergency resuscitative thoracotomy; GCS, Glasgow Coma Scale; HR, heart rate; IQR, Interquartile range; ISS, Injury Severity Score; REBOA, resuscitative endovascular balloon occlusion of the aorta; RR, respiratory rate; SBP, systolic blood pressure; TAE, transarterial embolization.

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Revision of ‘golden hour’ for hemodynamically unstable trauma patients: an analysis of nationwide hospital-based registry in Japan
Kazuhiro Okada, Hisashi Matsumoto, Nobuyuki Saito, Takanori Yagi, Mihye Lee
Trauma Surg Acute Care Open Mar 2020, 5 (1) e000405; DOI: 10.1136/tsaco-2019-000405

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Revision of ‘golden hour’ for hemodynamically unstable trauma patients: an analysis of nationwide hospital-based registry in Japan
Kazuhiro Okada, Hisashi Matsumoto, Nobuyuki Saito, Takanori Yagi, Mihye Lee
Trauma Surg Acute Care Open Mar 2020, 5 (1) e000405; DOI: 10.1136/tsaco-2019-000405
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Revision of ‘golden hour’ for hemodynamically unstable trauma patients: an analysis of nationwide hospital-based registry in Japan
Kazuhiro Okada, Hisashi Matsumoto, Nobuyuki Saito, Takanori Yagi, Mihye Lee
Trauma Surgery & Acute Care Open Mar 2020, 5 (1) e000405; DOI: 10.1136/tsaco-2019-000405
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