Intraoperative vasopressor use during emergency surgery on injured meth users

Article Figures & Data

Table 1

Characteristics of patients who received no vasopressors compared with those who received any vasopressors during operation

Factor	No vasopressor (n=60)	1 or more vasopressor doses (n=32)	P value
Age	31 (±18)	37 (±17)	0.045
Male gender, n (%)	45 (75)	26 (81)	0.496
White race, n (%)	58 (96)	32 (100)	0.580
Polysubstance on UDS, n (%)	51 (85)	28 (87)	0.743
Mechanism of injury, penetrating, n (%)	21 (35)	19 (59)	0.025
ISS (continuous)	12 (±13)	13.5 (±12)	0.708
ISS categories and scores: (n, % within group)			0.305
Mild (<9)	10 (16)	8 (19)
Moderate (9–15)	26 (43)	9 (28)
Severe (16–25)	15 (25)	12 (44)
Profound (>25)	9 (15)	3 (9)
OR duration	2.5 (±9)	2.75 (±7.5)	0.760
ASA class, n (% within group)			<0.01
1	2 (3.3)	0 (0)
2	30 (50)	7 (21)
3	12 (20)	17 (53)
4	7 (11)	5 (15)
5	9 (15)	3 (9)
Emergent OR, n (%)	36 (60)	24 (75)	0.150
Intubation prior to OR, n (%)	20 (33)	11 (34)	0.920

ASA, American Society of Anesthesiologists; ISS, Injury Severity Score; OR, Operating Room ; UDS, urine drug screen.

Table 2

Hemodynamic variables of patients who received vasopressors in the operating room compared with those who did not

Factor	No vasopressor (n=60)	1 or more vasopressor doses (n=32)	P value
Preoperative MAP	85 (±19)	85 (±127)	0.718
Base deficit on initial VBG/ABG	−0.3 (IQR 5)	−3 (IQR 22)	0.02
Transfused, n (%)	12 (20)	8 (40)	0.580
Transfusion, number of units of product	0 (±24)	0 (±15)	0.605
EBL	100 (±325)	200 (±249)	0.230
EKG changes requiring treatment	0	3 (9.4)	0.016
20% change in MAP	33 (55)	26 (81)	0.012
MAP change requiring treatment, n (%)	14 (23)	23 (71)	<0.001

ABG, arterial blood gas; EBL, estimated blood loss; EKG, electrocardiogram; MAP, mean arterial pressure; VBG, venous blood gas.

Table 3

OR for one or more vasopressor doses

ASA, American Society of Anesthesiologists; MAP, Mean Arterial Pressure; MOI, mechanism of injury.