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Open Access

Protective/reparative cytokines are suppressed at high injury severity in human trauma

Jinman Cai, Todd McKinley, Isabel Billiar, Mazen S Zenati, Greg Gaski, Yoram Vodovotz, Danielle S Gruen, Timothy R Billiar, Rami A Namas
DOI: 10.1136/tsaco-2020-000619 Published 2 March 2021
Jinman Cai
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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Todd McKinley
2Department of Orthopedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA
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Isabel Billiar
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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Mazen S Zenati
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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Greg Gaski
3Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church, Virginia, USA
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Yoram Vodovotz
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
4Center for Inflammation and Regenerative Modeling, University of Pittsburgh McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania, USA
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Danielle S Gruen
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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  • ORCID record for Danielle S Gruen
Timothy R Billiar
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
4Center for Inflammation and Regenerative Modeling, University of Pittsburgh McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania, USA
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Rami A Namas
1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
4Center for Inflammation and Regenerative Modeling, University of Pittsburgh McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania, USA
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Article Information

vol. 6 no. 1
DOI 
https://doi.org/10.1136/tsaco-2020-000619

Online ISSN 
2397-5776
History 
  • Received October 7, 2020
  • Revised February 4, 2021
  • Accepted February 6, 2021
  • Published online March 2, 2021.

Copyright & Usage 
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Author Information

  1. Jinman Cai1,
  2. Todd McKinley2,
  3. Isabel Billiar1,
  4. Mazen S Zenati1,
  5. Greg Gaski3,
  6. Yoram Vodovotz1,4,
  7. Danielle S Gruen1,
  8. Timothy R Billiar1,4,
  9. Rami A Namas1,4
  1. 1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
  2. 2Department of Orthopedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA
  3. 3Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church, Virginia, USA
  4. 4Center for Inflammation and Regenerative Modeling, University of Pittsburgh McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania, USA
  1. Correspondence to Dr Rami A Namas; namasra2{at}upmc.edu
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Protective/reparative cytokines are suppressed at high injury severity in human trauma
Jinman Cai, Todd McKinley, Isabel Billiar, Mazen S Zenati, Greg Gaski, Yoram Vodovotz, Danielle S Gruen, Timothy R Billiar, Rami A Namas
Trauma Surg Acute Care Open Mar 2021, 6 (1) e000619; DOI: 10.1136/tsaco-2020-000619

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Protective/reparative cytokines are suppressed at high injury severity in human trauma
Jinman Cai, Todd McKinley, Isabel Billiar, Mazen S Zenati, Greg Gaski, Yoram Vodovotz, Danielle S Gruen, Timothy R Billiar, Rami A Namas
Trauma Surg Acute Care Open Mar 2021, 6 (1) e000619; DOI: 10.1136/tsaco-2020-000619
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Protective/reparative cytokines are suppressed at high injury severity in human trauma
Jinman Cai, Todd McKinley, Isabel Billiar, Mazen S Zenati, Greg Gaski, Yoram Vodovotz, Danielle S Gruen, Timothy R Billiar, Rami A Namas
Trauma Surgery & Acute Care Open Mar 2021, 6 (1) e000619; DOI: 10.1136/tsaco-2020-000619
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