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Open Access

Direct discharge from the emergency department of simple stable injuries: a propensity score-adjusted non-inferiority trial

Thijs H Geerdink, Simone Augustinus, Jasper J Groen, Johanna M van Dongen, Robert Haverlag, Ruben N van Veen, J Carel Goslings
DOI: 10.1136/tsaco-2021-000709 Published 14 April 2021
Thijs H Geerdink
1Department of Trauma Surgery, OLVG, Amsterdam, The Netherlands
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Simone Augustinus
1Department of Trauma Surgery, OLVG, Amsterdam, The Netherlands
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Jasper J Groen
1Department of Trauma Surgery, OLVG, Amsterdam, The Netherlands
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Johanna M van Dongen
2Department of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Robert Haverlag
1Department of Trauma Surgery, OLVG, Amsterdam, The Netherlands
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Ruben N van Veen
1Department of Trauma Surgery, OLVG, Amsterdam, The Netherlands
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J Carel Goslings
1Department of Trauma Surgery, OLVG, Amsterdam, The Netherlands
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Figures

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  • Figure 1
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    Figure 1

    Timeline depicting patient inclusion and assessments of outcomes. DD, direct discharge; EPR, electronic patient record; PREM, patient-reported experience measure; PROM, patient-reported outcome measure.

  • Figure 2
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    Figure 2

    Flow chart depicting the inclusion of patients. In the DD cohort, patients in the emergency department with SSI were used to assess implementation. Patients who provided informed consent were used to assess healthcare utilization, and patients who completed the survey were used to assess patient-reported outcomes and experiences. DD, direct discharge; PREM, patient-reported experience measure; PROM, patient-reported outcome measure; SSI, simple stable injury.

  • Figure 3
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    Figure 3

    Depiction of differences in satisfaction with treatment, functional outcome, and healthcare utilization before and after direct discharge. DD, direct discharge; LEFS, Lower Extremity Functional Scale; PROMIS, Patient-Reported Outcomes Measurement Information System; QuickDASH, Shortened Version of the Disabilities of the Arm, Shoulder and Hand.

Tables

  • Figures
  • Table 1

    Simple and stable injuries, criteria and immobilization

    InjuryPediatric/adultCriteriaImmobilization after DD
    Pediatric clavicle FxPediatric
    • Age ≤14.

    • No indication for surgical treatment.

    • Sling.

    Radial head/neck FxAdult
    • Head: Mason type 1; neck: undisplaced.

    • Or positive fat pad sign.

    • Pressure bandage, sling.

    Greenstick or torus/buckle-type Fx of the distal radiusPediatric
    • Acceptable angulation-based residual growth.

    • Torus/buckle type: isolated ulna Fx, isolated radius Fx, or both.

    • Greenstick type: isolated ulna Fx or isolated radius Fx.

    • Removable wrist brace.

    Fifth metacarpal neck FxAdult
    • Volar angulation <70°.

    • No rotational deviation.

    • Buddy strap and pressure bandage.

    Mallet fingerAdult
    • Either bony or tendinous.

    • Treated conservatively.

    • Mallet splint.

    Weber A-type ankle FxAdult
    • Dislocation <2 mm.

    • No signs of stage 2 supination-adduction-type injury.

    • Tubigrip and ankle brace.

    Avulsion-type ankle FxAdult
    • Either lateral or medial malleolus or tarsal bones.

    • Tubigrip and ankle brace.

    Fx of fifth metatarsal baseAdult
    • Fx located in either zone 1 or zone 2.

    • Dislocation ≤4 mm.

    • Walker boot.

    Fx of greater toeBoth
    • Either proximal or distal phalanx Fx.

    • Undisplaced.

    • Spica pressure bandage and bandage shoe.

    Fx of lesser toeBoth
    • Any isolated Fx.

    • No indication for surgical treatment.

    • Buddy strap.

    Bicycle spoke injuryPediatric
    • No Fx based on radiograph.

    • Superficial wound.

    • Pressure bandage.

    • DD, direct discharge; Fx, fracture.;

  • Table 2

    Different questionnaires used to assess satisfaction, functional outcome, and quality of life

    OutcomeExtremityAge categoryNumber of itemsSummary scoreNon-inferiority margin (MCID)
    Satisfaction with treatmentEitherAll participants1 item; 0–100 VASRating scale (0–10*)−0.7 points
    Functional outcome
     No questionnaireEither0–3  
     PROMIS UE SFUpper4–178 items; 5P LikertT-scoreNot available
     PROMIS Mobility SFLower4–178 items; 5P LikertT-score−3.0 points
     QuickDASHUpper≥1811 items; 5P LikertTotal (100–0*)+15.91 points
     LEFSLower≥1820 items; 5P LikertTotal (0–80*)−9.0 points
    Health-related QoL
     No questionnaireEither0–3  
     EQ-5D-YouthEither4–11, and 12–17 (if proxy)5 items; 3 levels,
    1 item; 0–100 VAS
    Index (0–1*)
    VAS score (0–100*)
     EQ-5D-5LEither≥18, and 12–17 (self-complete)5 items; 3 levels,
    1 item; 0–100 VAS
    Index (0–1*)
    VAS score (0–100*)
    • Summary scores were calculated using the guideline of each corresponding questionnaire. Normative Dutch values of the EQ-5D-5L were used to calculate the EQ-5D-5L index scores, and normative values of the EQ-5D-3L were used to calculate the EQ-5D-Youth index scores.

    • T-score: 50 points equal to mean score of the reference population and −10 equal to the mean score of −1 SD compared with reference.

    • *Indicates best outcome score.

    • EQ-5D-3L, EuroQol-5-dimension 3-level questionnaire; EQ-5D-5L, EuroQol-5-dimension 5-level questionnaire; 5L, 5-level; LEFS, Lower Extremity Functional Scale; MCID, minimal clinically important difference; 5P, 5-point; PROMIS, Patient-Reported Outcomes Measurement Information System; QoL, quality of life; QuickDASH, Shortened Version of the Disabilities of the Arm, Shoulder and Hand; SF, Short Form; UE, upper extremity; VAS, Visual Analog Scale.

  • Table 3

    Baseline characteristics of participating patients

    CharacteristicsProvided informed consent (n=719)Completed the survey (n=297)
    Pre-DD (n=348)DD (n=371)Pre-DD (n=144)DD (n=153)
    Age, median (IQR)24 (10–45)28 (10–48)26 (11–55)36 (13–54)
    Age <18 years, n (%)142 (40.8)135 (36.4)59 (41.0)48 (31.4)
    Gender male, n (%)194 (55.7)197 (53.1)76 (52.8)68 (44.4)
    Type of injury, n (%)
     Pediatric clavicle Fx13 (3.7)17 (4.6)8 (5.6)8 (5.2)
     Radial head/neck Fx61 (17.5)56 (15.1)24 (16.7)28 (18.3)
     Pediatric Fx distal radius
      Greenstick47 (13.5)25 (6.7)15 (10.4)9 (5.9)
      Torus58 (16.7)48 (12.9)21 (14.6)18 (11.8)
     Fifth metacarpal neck Fx25 (7.2)11 (3.0)6 (4.2)1 (0.7)
     Mallet finger19 (5.5)8 (2.2)6 (4.2)4 (2.6)
     Weber A-type ankle Fx20 (5.7)21 (5.7)11 (7.6)14 (9.2)
     Avulsion-type ankle Fx10 (2.9)32 (8.6)8 (5.6)12 (7.8)
     Fx of fifth metatarsal base46 (13.2)51 (13.7)17 (11.8)20 (13.1)
     Fx of greater toe19 (5.5)36 (9.7)10 (6.9)11 (7.2)
     Fx of lesser toe16 (4.6)34 (9.2)10 (6.9)18 (11.8)
     Bicycle spoke injury14 (4.0)32 (8.6)8 (5.6)10 (6.5)
    Region, age category, functional outcome questionnaire, n (%)
     UE, age 0–3, none7 (2.0)11 (3.0)3 (2.1)4 (2.6)
     LE, age 0–3, none2 (0.6)4 (1.1)0 (0.0)1 (0.7)
     UE, pediatric, PROMIS UE112 (32.2)81 (21.8)41 (28.5)31 (20.3)
     LE, pediatric, PROMIS Mobility21 (6.0)39 (10.5)15 (10.4)12 (7.8)
     UE, adult, QuickDASH104 (29.9)73 (19.7)36 (25.0)33 (21.6)
     LE, adult, LEFS102 (29.3)163 (43.9)49 (34.0)72 (47.1)
    Employment status, n (%)
     Going to work––58 (40.3)73 (47.7)
     Going to school––59 (41.0)44 (28.8)
     No work/school––27 (18.8)36 (23.5)
    • DD, direct discharge; Fx, fracture; LE, lower extremity; LEFS, Lower Extremity Functional Scale; PROMIS, Patient-Reported Outcomes Measurement Information System; QuickDASH, Shortened Version of the Disabilities of the Arm, Shoulder and Hand; UE, upper extremity.

  • Table 4

    Patient-reported outcomes and experiences at 3 months

    OutcomeResponse, nDescriptive outcomeEffect (regression DD vs. pre-DD)Non-inferior
    Pre-DDDDPre-DDDDDifference, mean (95% CI)Significance, p value
    Continuous data, mean (SD)
    Satisfaction (VAS 0–100)1441538.13 (1.5)7.95 (1.7)−0.16 (−0.53 to 0.21)0.408Yes
    Pain (VAS 0–100)1441531.40 (2.1)1.52 (1.9)0.078 (−0.37 to 0.53)0.727–
    Functional outcome14114877.4 (26.4)81.0 (21.9)3.98 (−1.56 to 9.37)0.166–
     QuickDASH363310.5 (12.2)13.2 (14.8)4.15 (−2.00 to 10.50)0.231Yes
     LEFS497263.1 (16.4)64.0 (15.4)1.06 (−4.56 to 6.81)0.716Yes
     PROMIS UE413135.3 (14.7)38.7 (13.6)3.79 (−3.40 to 10.88)0.270NA
     PROMIS Mobility151244.0 (12.5)54.1 (7.4)10.79 (2.78 to 19.67)0.019Yes
    Health-related QoL
     EQ-5D-5L index851050.839 (0.189)0.852 (0.139)0.014 (−0.032 to 0.062)0.553–
     EQ-5D-5L VAS8510580.2 (16.7)80.3 (13.1)0.19 (−4.1 to 4.4)0.932–
     EQ-5D-Youth index56430.874 (0.242)0.949 (0.148)0.076 (0.003 to 0.156)0.052–
     EQ-5D-Youth VAS564392.3 (9.6)94.7 (7.5)2.4 (−1.0 to 5.8)0.169–
    Dichotomous data, n (%)OR (95% CI) 
    Dissatisfied with treatment (Likert)1441535 (3.5)11 (7.2)2.05 (0.69 to 6.09)0.197–
    Treatment preference DD14415357 (39.6)125 (81.7)6.72 (3.95 to 11.41)<0.001–
    • Propensity score-adjusted linear regression was performed to analyze continuous data with bootstrapping for non-normal distribution and binary logistic to analyze dichotomous data.

    • Non-inferiority margins: satisfaction −0.7; QuickDASH +15.91; LEFS −9.0; PROMIS Mobility −3.0.

    • A p value <0.05 was considered statistically significant.

    • DD, direct discharge; EQ-5D-5L, EuroQol-5-dimension 5-level questionnaire; LEFS, Lower Extremity Functional Scale; NA, not available; PROMIS, Patient-Reported Outcomes Measurement Information System; QoL, quality of life; QuickDASH, Shortened Version of the Disabilities of the Arm, Shoulder and Hand; UE, upper extremity; VAS, Visual Analog Scale.

  • Table 5

    Resource utilization

    OutcomePatients, nDescriptive outcomeEffect (regression DD vs. pre-DD)
    Pre-DDDDPre-DDDDDifference, mean (95% CI)Significance, p value
    Survey at 3 months 
    Return-to-sports (days), mean (SD)908029.2 (24.7)26.6 (25.3)−3.49 (−10.61 to 3.97)0.372
    Return-to-work (days), mean (SD)587313.3 (21.0)9.1 (14.8)−0.165 (−4.91 to 1.44)0.313
    Return-to-school (days), mean (SD)59442.3 (3.4)1.9 (2.1)−0.43 (−0.17 to 0.59)0.456
     OR (95% CI)
    Visited general practitioner, n (%)14415334 (23.6)40 (26.1)1.08 (0.63 to 1.85)0.784
    Visited physiotherapist, n (%)14415338 (26.4)32 (20.9)0.70 (0.41 to 1.21)0.197
    Missed school for follow-up, n (%)594434 (57.6)5 (11.4)0.084 (0.028 to 0.253)<0.001
    Missed work for follow-up, n (%)587326 (44.8)6 (8.2)0.110 (0.041 to 0.296)<0.001
    EPR evaluation (range 14–26 months)Difference, mean (95% CI)
    Number of hospital visits, mean (SD)3483711.80 (1.13)0.14 (0.47)−1.68 (−1.81 to −1.55)<0.001
     With physician1.62 (0.94)0.11 (0.44)−1.53 (−1.65 to −1.42)<0.001
     With plaster technician0.18 (0.51)0.05 (0.26)−0.13 (−0.19 to −0.07)<0.001
    Imaging during follow-up, mean (SD)348371 
     X-ray0.30 (0.65)0.05 (0.32)−0.26 (−0.33 to 0.18)<0.001
     CT scan0.00.01 (0.07)NP–
     MRI scan0.00.0NP–
    No-shows, n (%)3483719 (2.6)0.0NP–
    • Propensity score-adjusted linear regression performed to analyze continuous data with bootstrapping for non-normal distribution and binary logistic to analyze dichotomous data.

    • A p value <0.05 was considered statistically significant.

    • DD, direct discharge; EPR, electronic patient record; NP, not performed (as the number of observations was too small to perform bootstrapping (if applicable) and subsequent regression).

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Direct discharge from the emergency department of simple stable injuries: a propensity score-adjusted non-inferiority trial
Thijs H Geerdink, Simone Augustinus, Jasper J Groen, Johanna M van Dongen, Robert Haverlag, Ruben N van Veen, J Carel Goslings
Trauma Surg Acute Care Open Apr 2021, 6 (1) e000709; DOI: 10.1136/tsaco-2021-000709

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Direct discharge from the emergency department of simple stable injuries: a propensity score-adjusted non-inferiority trial
Thijs H Geerdink, Simone Augustinus, Jasper J Groen, Johanna M van Dongen, Robert Haverlag, Ruben N van Veen, J Carel Goslings
Trauma Surg Acute Care Open Apr 2021, 6 (1) e000709; DOI: 10.1136/tsaco-2021-000709
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Direct discharge from the emergency department of simple stable injuries: a propensity score-adjusted non-inferiority trial
Thijs H Geerdink, Simone Augustinus, Jasper J Groen, Johanna M van Dongen, Robert Haverlag, Ruben N van Veen, J Carel Goslings
Trauma Surgery & Acute Care Open Apr 2021, 6 (1) e000709; DOI: 10.1136/tsaco-2021-000709
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