Case 1: a 50-year-old man with colon cancer 36 months from resection and adjuvant chemotherapy with a single point of obstruction in the terminal ileum. He has a single, 3 cm metastatic lesion in his liver, but no other metastatic disease. |
Base scenario | 94.94 (4.70±0.64) | 95.80 (4.83±0.48) | 94.42 (4.62±0.71) | 0.587 |
Multiple hepatic metastases | 82.91 (4.16±0.97) | 91.60 (4.48±0.72) | 77.66 (3.97±1.04) | 0.001 |
Pulmonary metastases | 71.84 (3.87±1.16) | 84.87 (4.31±0.83) | 63.96 (3.60±1.24) | <0.001 |
Shorter disease-free interval | 86.08 (4.29±0.84) | 87.39 (4.39±0.78) | 85.28 (4.23±0.87) | 0.599 |
Omental metastases | 63.92 (3.68±1.11) | 78.15 (4.05±0.95) | 55.33 (3.46±1.15) | <0.001 |
Pancreatic adenocarcinoma | 46.84 (3.22±1.24) | 47.06 (3.24±1.22) | 46.70 (3.22±1.26) | 0.951 |
Case 2: a 45-year-old woman with epithelial ovarian cancer 36 months from optimal debulking and adjuvant chemotherapy with a single point of obstruction in the small bowel from carcinomatosis. She has three peritoneal implants, but no other metastatic disease. |
Base scenario | 74.48 (3.97±1.12) | 90.18 (4.29±0.86) | 64.61 (3.60±1.19) | <0.001 |
Ascites present | 57.24 (3.41±1.19) | 74.11 (3.81±1.04) | 46.63 (3.16±1.21) | <0.001 |
Multiple areas of obstruction | 22.76 (2.54±1.17) | 26.79 (2.65±1.13) | 20.22 (2.48±1.18) | 0.194 |
2nd episode of obstruction | 24.48 (2.63±1.14) | 25.00 (2.63±1.07) | 24.16 (2.65±1.18) | 0.871 |
Shorter disease-free interval | 47.59 (3.24±1.13) | 50.00 (3.29±1.03) | 46.07 (3.22±1.18) | 0.514 |
Melanoma | 73.10 (3.88±1.15) | 87.50 (4.27±0.99) | 64.04 (3.63±1.19) | <0.001 |
Case 3: a 62-year-old woman with a carcinoid tumor 48 months from resection of an isolated mesenteric mass with a single point of obstruction in the jejunum from an unresectable central mesenteric mass. |
Base scenario | 83.88 (4.21±0.93) | 90.99 (4.50±0.74) | 79.01 (4.01±0.99) | 0.008 |
Stable hepatic metastases | 75.09 (3.94±1.00) | 87.39 (4.33±0.81) | 66.67 (3.67±1.03) | <0.001 |
2nd episode of obstruction | 44.69 (3.22±1.11) | 54.95 (3.41±1.03) | 37.65 (3.08±1.15) | 0.005 |
Shorter disease-free interval | 32.97 (2.82±1.23) | 36.94 (2.91±1.25) | 30.25 (2.76±1.21) | 0.248 |
Multiple areas of obstruction | 32.60 (2.90±1.15) | 39.64 (3.09±1.12) | 27.78 (2.78±1.15) | 0.04 |