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Open Access

Trauma and syncope: looking beyond the injury

Kieran S Kavi, Nicholas P Gall
DOI: 10.1136/tsaco-2022-001036 Published 2 February 2023
Kieran S Kavi
1Department of Emergency Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK
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Nicholas P Gall
2Department of Cardiology, King's College Hospital NHS Foundation Trust, London, UK
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  • Figure 1
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    Figure 1

    Classifications of TLoC and syncope. TLoC can be broadly categorized into a traumatic and non-traumatic loss of consciousness, with non-traumatic further subdivided into four groups: syncope, psychogenic pseudo-syncope, epileptic seizures, and rare miscellaneous causes. Syncope is categorized into four types: reflex, cardiac, orthostatic hypotension, and unexplained syncope. Their relative mean frequencies are stated.11 TLoC, transient loss of consciousness.

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    Figure 2

    Algorithm for the management of falls and syncope evaluation. Credit to ‘Syncope, “mechanical falls”, and the trauma surgeon’ by Biffl et al.16 Consent for image use provided by Wolters Kluwer health (CC-BY-NC). The discussion points A–F and table 1 can be sourced from the original article.

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    Figure 3

    Venn diagram of the ESC, ACC, and NICE high-risk syncope features. A Venn diagram illustrating which high-risk features indicative of cardiac syncope are recognized by NICE, ACC, and ESC guidance. CHADS-2 estimates stroke risk in patients with atrial fibrillation; ACC, American College of Cardiology; BPM, beats per minute; CAD, coronary artery disease; ED, emergency department; ESC, European Society of Cardiology; GFR, glomerular filtration rate; NICE, National Institute for Health and Care Excellence; SBP, systolic blood pressure; SCD, sudden cardiac death; TLoC, transient loss of consciousness.

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    Figure 4

    A systematic outline of ATLS principles. ATLS, advanced trauma life support.

Tables

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  • Table 1

    Causes of syncope

    Pathophysiological originCauses
    Reflex syncopeVasovagal
    Situational
    Carotid sinus syndrome
    Non-classical forms
    Cardiac syncopeWith obstructive structural heart disease:
    Aortic stenosis
    Hypertrophic cardiomyopathy
    Cardiac masses
    Pericardial disease/tamponade
    Prosthetic valvular dysfunction
    Congenital coronary artery abnormalities
    With arrhythmia:
    Tachyarrhythmias
    Bradyarrhythmias
    Cardiopulmonary and great vessels:
    Pulmonary embolism
    Aortic dissection
    Pulmonary hypertension
    Orthostatic hypotensionMedication induced
    Volume depletion
    Primary autonomic failure
    Secondary autonomic failure
    • The categorizations and causes of syncope, modified from the European Society of Cardiology.32

  • Table 2

    Non-syncopal conditions presenting with collapse

    ConditionFeatures that distinguish from syncope
    Cardiac arrestNo spontaneous recovery from TLoC
    CataplexyLoss of muscular tone and responsive, usually associated with narcolepsy
    ComaLonger duration of LoC without spontaneous recovery
    Complex partial seizures, absence epilepsyUnresponsiveness and amnesia without falls, with associated neurological features
    Falls without TLoCAbsence of amnesia and unresponsiveness, clear cause for fall
    Generalized seizuresAura, flashing lights may trigger, longer duration of LoC, symmetrical rhythmic muscle movements, confusion after LoC lasting minutes (shorter with syncope)
    IntoxicationLonger duration of LoC, consciousness often impaired rather than lost
    Intracerebral or subarachnoid hemorrhageSevere headache, neurological signs, and progressive LoC
    Metabolic disorders (hypoglycaemia, hypoxia, hyperventilation with hypocapnia)Longer duration of LoC, consciousness often impaired rather than lost
    Psychogenic pseudosyncopeIncreased frequency and longer duration of apparent syncope without true LoC, maintained hemodynamics, normal electroencephalogram
    Subclavian steal syndromeUpper extremity activity associated with focal neurological signs
    Transient ischemic attackFocal neurological features usually without TLoC.
    If LoC occurs, there is a longer duration of TLoC.
    • Conditions that may be incorrectly diagnosed as syncope are listed, modified from the American College of Cardiology and European Society of Cardiology and syncope guidelines.12 32

    • LoC, loss of consciousness; TLoC, transient loss of consciousness.

  • Table 3

    Canadian Syncope Risk Score

    CategoryRisk factorsPoints
    Clinical evaluationPredisposition to vasovagal symptoms−1
    History of heart disease*1
    Any systolic blood pressure reading <90 or >180 mm Hg2
    InvestigationsElevated troponin level (>99th percentile)2
    Abnormal QRS axis (<−30° or >100°)1
    QRS duration >130 ms1
    Corrected QT interval >480 ms2
    Diagnosis in the EDVasovagal syncope−2
    Cardiac syncope2
    Total scoreVery low risk: −3 to −2
    Low risk: −1 to 0
    Medium risk: 1–3
    High risk: 4–5
    Very high risk: 6–11
    • The risk factors included in the Canadian Syncope Risk Score and their associated points that categorize patients into groups from very low risk to very high risk of serious adverse outcomes after 30 days.

    • *History of heart disease includes coronary or valvular heart disease, cardiomyopathy, heart failure and non-sinus rhythm on ECG (ECG evidence during index visit or documented history of ventricular or atrial arrhythmias, or device implantation).

    • ED, emergency department.

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Trauma and syncope: looking beyond the injury
Kieran S Kavi, Nicholas P Gall
Trauma Surg Acute Care Open Feb 2023, 8 (1) e001036; DOI: 10.1136/tsaco-2022-001036

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Trauma and syncope: looking beyond the injury
Kieran S Kavi, Nicholas P Gall
Trauma Surg Acute Care Open Feb 2023, 8 (1) e001036; DOI: 10.1136/tsaco-2022-001036
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Trauma and syncope: looking beyond the injury
Kieran S Kavi, Nicholas P Gall
Trauma Surgery & Acute Care Open Feb 2023, 8 (1) e001036; DOI: 10.1136/tsaco-2022-001036
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  • Article
    • Abstract
    • Introduction
    • Syncope and the trauma team
    • Definitions
    • Causes of syncope
    • Assessment of syncope
    • Should investigations be protocol driven?
    • Which international syncope guideline to follow?
    • Risk stratification
    • How can trauma be managed differently to prevent recurrent syncope and future trauma?
    • Conclusion
    • Ethics statements
    • Footnotes
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