PT - JOURNAL ARTICLE AU - Paul B McBeth AU - Jordan A Weinberg AU - Babak Sarani AU - Louise Y Y Yeung AU - Addison K May TI - A surgeon's guide to anticoagulant and antiplatelet medications part one: warfarin and new direct oral anticoagulant medications AID - 10.1136/tsaco-2016-000020 DP - 2016 Jul 01 TA - Trauma Surgery & Acute Care Open PG - e000020 VI - 1 IP - 1 4099 - http://tsaco.bmj.com/content/1/1/e000020.short 4100 - http://tsaco.bmj.com/content/1/1/e000020.full AB - An increasing number of potent antiplatelet and anticoagulant medications are being used for the long-term management of cardiac, cerebrovascular, and peripheral vascular conditions. Management of these medications in the perioperative and peri-injury settings can be challenging for surgeons, mandating an understanding of these agents and the risks and benefits of various management strategies. In this two-part review, agents commonly encounter by surgeons in the perioperative and peri-injury settings are discussed and management strategies for patients on long-term antiplatelet and anticoagulant therapy reviewed. In part I, we review warfarin and the new direct oral anticoagulants. In part II, we review antiplatelet agents and assessment of platelet function and the perioperative management of long-term anticoagulant and antiplatelet therapy.