Demographics baseline
| TXA indicated (n=217) | TXA not indicated (n=183) | p Value | |
| Age | 45.5 | 42.1 | 0.57 |
| Male (%) | 73.3% | 82.5% | 0.27 |
| Blunt mechanism (%) | 70.0% | 89.1% | 0.0001 |
| Penetrating mechanism (n) | 30.0% | 10.9% | 0.0001 |
| % Patients receiving blood product | 65.9% | 7.1% | 0.0001 |
| Mean PRBC units (if received blood product) | 6.9 U | 3.1 U | 0.13 |
| Mean ISS | 21 | 14 | >0.0001 |
| ISS ≥15 (%) | 65.90% | 44.30% | >0.0001 |
| Mean arrival SBP (mm Hg) | 109.8 | 140.6 | >0.001 |
| Arrival lactate* | 3.2 | 2.4 | >0.001 |
*Arrival lactate available for 337 patients.
ISS, injury severity score; PRBC, packed red blood cell; TXA, tranexamic acid.