Table 5

Successful administration of high-flow oxygen therapy at the intermediate care unit.

Total*Successful
(transfer to OR/ward)
Unsuccessful
(transfer to ICU)
76 (79.2%)18 (18.8%)
n (%)Missing, n (%)n (%)Missing, n (%)
Indication to start high-flow oxygen therapy0 (0%)0 (0%)
 Pulmonary49 (64.5%)16 (88.9%)
 Postweaning (from ICU or OR)15 (19.7%)0 (0.0%)
 Sepsis (no focus in lungs)7 (9.2%)0 (0.0%)
 Post-trauma5 (6.6%)2 (11.1%)
Underlying diagnosis of admission0 (0%)0 (0%)
 Trauma25 (32.89%)10 (55.56%)
 Postoperative abdominal surgery22 (28.95%)4 (22.22%)
 Esophagectomy surgery14 (18.42%)1 (5.56%)
 Extra-abdominal surgery7 (9.21%)0 (0.0%)
 Other4 (5.26%)2 (11.11%)
 Severe necrotizing soft tissue disease2 (2.63%)1 (5.56%)
 Exchange bed2 (2.63%)0 (0.0%)
Vital parameters10 (13.2%)0 (0%)
 Heart rate94.14 (90.06, 98.71)99.28 (89.33, 112.78)
 Mean arterial pressure93.86 (89.74, 98.07)91.06 (84.07, 98.11)
 Respiratory rate19.83 (18.08, 21.86)20.67 (18.50, 23.17)
 SpO293.64 (93.03, 94.27)93.17 (92.11, 94.33)
Arterial blood gas23 (30.3%)1 (5.6%)
 pH7.42 (7.40, 7.43)7.40 (7.37, 7.42)
 pCO239.40 (37.74, 41.30)40.06 (37.83, 43.00)
 pO273.75 (70.00, 78.44)69.29 (63.25, 82.56)
 HCO324.93 (23.91, 25.87)24.22 (22.43, 25.71)
 BE0.42 (−0.80, 1.52)−0.77 (−2.98, 0.93)
 Std. HCO324.97 (23.97, 25.86)24.29 (22.58, 25.51)
 Saturation0.94 (0.93, 0.95)0.93 (0.92, 0.94)
Laboratory investigations
 CRP152.44 (130.45, 176.97)8 (10.5%)202.59 (164.27, 246.94)1 (5.6%)
 Leukocyte count12.90 (11.60, 14.47)7 (9.2%)12.90 (10.22, 15.35)0 (0%)
  • This table shows the indication to start high-flow nasal cannula oxygen therapy, underlying diagnoses, vital parameters and arterial blood gas measures for both patients for whom high-flow nasal cannula oxygen therapy was successfully and unsuccessfully administered.

  • Percentages are shown per column and CIs are 95% bias-corrected and accelerated CIs.

  • *The total does not add up to 100%, since there were two deaths at the IMCU, which were excluded from these analyses.

  • CRP, C reactive protein; IMCU, intermediate care unit; OR, operating room.