Clinical outcomes of patients with (non-) Group A Streptococcus necrotizing fasciitis
| Total | GAS necrotizing fasciitis | Non-GAS necrotizing fasciitis | P value | |
| n=81 (100%) | n=38 (47%) | n=43 (53%) | ||
| Total number of operations (median, IQR)* | 3 (4) | 2 (2) | 2 (1) | 0.756 |
| Amputation | 15 (19%) | 8 (21%) | 7 (16%) | 0.581 |
| Hospital length of stay (median, IQR) | 31 (35) | 31 (33) | 32 (47) | 0.721 |
| ICU admittance | 68 (84%) | 35 (92%) | 33 (77%) | 0.06 |
| ICU length of stay (median days, IQR)† | 5 (11) | 6 (12) | 4 (8) | 0.406 |
| Pneumonia‡ | 16 (25%) | 12 (39%) | 4 (13%) | 0.017 |
| Time between diagnosis and pneumonia (median days, IQR) | 11 (19) | 10 (9) | 33 (43) | 0.063 |
| Mortality | 26 (32%) | 7 (18%) | 19 (44%) | 0.013 |
| Died within 5 days after necrotizing fasciitis diagnosis | 18 (69%) | 7 (100%) | 11 (58%) | 0.439 |
| Time between diagnosis and death (median days, IQR) | 3 (9) | 1 (2) | 4 (14) | 0.055 |
Bold font denotes significant p value.
*1 (1%) missing case.
†13 (16%) missing cases.
‡All patients who died within 5 days after necrotizing fasciitis diagnosis were excluded from this analysis.
GAS, Group A Streptococcus; ICU, intensive care unit.