Demographic data with breakdown by VTE diagnosis and univariate analysis
| Total (n=549) | No VTE (n=430) | VTE (n=119) | P value | |
| TESS | 9 (5–11) | 8 (4–9) | 10 (9–11) | <0.0001* |
| Age (years) | 23 (21–27) | 23 (21–26) | 23 (21–27) | 0.81 |
| Male, n (%) | 546 (99.5) | 428 (99.5) | 118 (99.1) | 0.52 |
| ISS | 21 (12–29) | 17 (10–27) | 29 (21–38) | <0.0001* |
| Simulated BMI (kg/m2) | 24.9 (22.9–27.1) | 25.0 (23.0–27.1) | 24.5 (22.6–26.9) | 0.32 |
| Mortality, n (%) | 6 (1.1) | 5 (1.2) | 1 (0.8) | 0.76 |
| Blast injury, n (%) | 441 (80.3) | 332 (77.2) | 109 (91.6) | 0.0002* |
| Penetrating mechanism, n (%) | 486 (88.5) | 375 (87.2) | 111 (93.3) | 0.09 |
| Lower extremity fracture, n (%) | 350 (63.8) | 253 (58.8) | 97 (81.5) | <0.0001* |
| Lower extremity amputation, n (%) | 222 (40.4) | 144 (33.5) | 78 (65.6) | <0.0001* |
| Ventilator days | 3 (0–7) | 2 (0–5) | 7 (5–10) | <0.0001* |
| Received blood transfusion, n (%) | 422 (76.9) | 309 (71.9) | 113 (95.0) | <0.0001* |
| Blood products administered (units) | 17 (2–47) | 10 (0–35) | 50 (28–86) | <0.0001* |
| Received massive transfusion within 24 hours, n (%) | 192 (35.0) | 116 (27.0) | 76 (63.9) | <0.0001* |
| Administered TXA, n (%) | 224 (40.8) | 142 (33.0) | 82 (68.9) | <0.0001* |
| Administered recombinant factor VII, n (%) | 19 (3.5) | 12 (2.8) | 7 (5.9) | 0.15 |
| Repair or ligation of vascular injury, n (%) | 159 (29.0) | 112 (26.1) | 47 (39.5) | 0.006* |
| Repair or ligation of venous injury, n (%) | 71 (12.9) | 48 (11.2) | 23 (19.3) | 0.03* |
| Pelvic fracture, n (%) | 72 (13.1) | 45 (10.5) | 27 (22.7) | 0.0008* |
| Head Abbreviated Injury Scale 3+, n (%) | 115 (21.0) | 89 (20.7) | 26 (21.9) | 0.88 |
| Spinal cord injury, n (%) | 23 (4.2) | 17 (4.0) | 6 (5.0) | 0.61 |
n (%) shown for categorical variables.
Median (IQR) shown for continuous variables.
*P<0.05.
BMI, body mass index; ISS, Injury Severity Score; TESS, Trauma Embolic Scoring System; TXA, tranexamic acid; VTE, venous thromboembolism.