ATC (n=88) | No ATC (n=457) | ||
Complication and event outcomes | % (95% CI) | % (95% CI) | p value |
Development of new or progressive MODS | 64.8 (54.8 to 74.8) | 7.7 (5.2 to 10.1) | <0.001 |
In-hospital mortality | 26.1 (17.6 to 36.5) | 0.4 (0 to 1) | <0.001 |
Developed of PARDS | 35.2 (25.1 to 45.5) | 3.5 (1.8 to 5.2) | <0.001 |
Readmission within 30 days of discharge | 1.2 (1.1 to 3.5) | 1.3 (0.3 to 2.4) | 0.92 |
Duration outcomes | Median days (IQR) | Median days (IQR) | p value |
Duration of hospitalization in survivors | 10 (7.7 to 12.3) | 3 (2.8 to 3.2) | <0.001 |
PICU-free days at day 28 | 17 (0 to 23) | 26 (25 to 28) | <0.001 |
Mechanical ventilator-free days at day 28 | 21 (0 to 27) | 28 (28 to 28) | <0.001 |
New or progressive MODS was defined by the Proulx et al criteria and excludes hematologic dysfunction.22 25 26 PARDS was defined by the pediatric acute lung injury consensus conference definition.27 The total number of survivors in patients with ATC and without ATC was 63 and 455, respectively. Those that died were considered to have 0 PICU-free days and 0 mechanical ventilator-free days at day 28.
ATC, acute traumatic coagulopathy; INR, international normalized ratio; IQR, interquartile range; MODS, multiple organ dysfunction syndrome; PARDS, pediatric acute respiratory distress syndrome; PICU, pediatric intensive care unit.