Table 1

Patient and injury characteristics—principal analysis cohort (n=501)

VariablePlasma groupP value
YOUNGOLD
Demographicsn=93n=137
 Age, years, mean (SD)45.7 (17.7)45.3 (17.2)0.84
 Male gender, No. (%)65 (70)99 (72)0.70
 Race, No. (%)0.21
  White88 (95)119 (87)
  Black4 (4)10 (7)
  Other0 (0)0 (0)
  Unknown0 (0)2 (1)
  Hispanic, No. (%)2 (2.3)4 (3.1)0.71
 Current smoking, No. (%)41 (54)42 (41)0.09
 Body mass index, mean (SD)30.7 (9.5)30.0 (6.5)0.58
Prehospital and injury
 Penetrating injury, No. (%)20 (22)26 (19)0.64
 Injury severity score, median (IQR)22.0 (13.0, 34.0)22.0 (16.0, 29.0)0.59
 Traumatic brain injury, No. (%)17 (36.2)19 (34.5)0.86
 Hospital transfer, No. (%)22 (23.7)30 (22.1)0.78
 Prehospital interval, median (IQR)3 (3.2)4 (2.9)0.89
Hospital
 Admission heart rate, mean (SD)105.2 (31.7)101.9 (28.9)0.41
 Admission systolic blood pressure, mean (SD)100.7 (39.2)100.7 (40.8)1.00
 Admission INR, median (IQR)1.2 (1.1, 1.4)1.2 (1.1, 1.3)0.58
 Admission hemoglobin, median (IQR)10.9 (9.0, 13.3)10.8 (9.4, 12.7)0.88
 Admission rapid thromboelastography
  Lysis at 30 min, %, median (IQR)0.1 (0.0, 1.4)0.2 (0.0, 1.1)0.75
  Max amplitude, min, median (IQR)59.6 (52.0, 63.5)56.4 (47.8, 64.7)0.48
  Alpha angle, degrees, median (IQR)70.8 (62.3, 74.9)70.2 (61.6, 74.7)0.60
  K-time, min, median (IQR)1.8 (1.2, 2.7)1.8 (1.2, 3.0)0.95
  Activated clotting time, median (IQR)113.0 (97.0, 136.0)113.0 (105.0, 136.0)0.46
 PRBC in 24 hours, median (IQR)3.0 (2.0, 6.0)2.0 (0.0, 7.0)0.35
 Plasma in 24 hours, median (IQR)0.0 (0.0, 3.0)0.0 (0.0, 3.0)0.90
 Platelets in 24 hours, median (IQR)0.0 (0.0, 1.0)0.0 (0.0, 1.0)0.63
 Crystalloid in 24 hours, median (IQR)4434 (2372, 6200)4375 (2200, 6600)0.96
 Multisystem organ failure, No. (%)61 (65.6)84 (61.3)0.51
  • No., number; PRBC, packed red blood cells.