Patient demographics and injury characteristics at baseline
| Baseline characteristics | No depression (n=4305) | Pre-existing depression (n=297) | P value |
| Age, median (IQR) years | 56 (33–76) | 51 (38–67) | 0.015* |
| Male, n (%) | 3158 (73) | 195 (66) | 0.005† |
| CCI, median (IQR) | 1 (0–4) | 1 (0–3) | 0.001* |
| ISS, median (IQR) | 25 (18–29) | 25 (18–29) | 0.929 |
| GCS score, median (IQR) | 15 (11–15) | 15 (13–15) | 0.326 |
| Most severely injured organ, n (%) | |||
| Head | 2465 (57) | 153 (52) | 0.098 |
| Chest | 671 (16) | 46 (15) | |
| Abdomen | 86 (2) | 4 (1) | |
| Limbs | 329 (8) | 26 (9) | |
| Multiple | 560 (13) | 53 (18) | |
| Spine | 162 (4) | 10 (3) | |
| Other | 32 (1) | 5 (2) | |
| Mechanism of injury, n (%) | |||
| Blast | 7 (0) | 0 (0) | <0.001‡ |
| Blow(s) without weapon | 321 (7) | 27 (9) | |
| Burn | 4 (0) | 1 (0) | |
| Crush | 32 (1) | 1 (0) | |
| Fall from less than 2 m | 1751 (41) | 110 (37) | |
| Fall from more than 2 m | 512 (12) | 62 (21) | |
| Road traffic collision | 1403 (33) | 63 (21) | |
| Gunshot wound | 32 (1) | 4 (1) | |
| Stabbing | 195 (5) | 21 (7) | |
| Other | 48 (1) | 8 (3) |
*Statistically significant using Mann-Whitney U test.
†Statistically significant using Fisher’s exact test.
‡Statistically significant using χ2 test.
CCI, Charlson Comorbidity Index; GCS, Glasgow Coma Scale; ISS, Injury Severity Score.