Comparison of laboratory values between overtransfused and non-overtransfused patients at four different phases of hospitalization
| Total (n=140) | Overtransfused (n=61) | Non-overtransfused (n=79) | P value | |
| Admission | ||||
| Hg (g/dL) | 12.6 (11.7) | 12.8 (11.7) | 12.0 (9.4) | 0.017 |
| Platelets | 242.0 (495.0) | 244.0 (351.0) | 239.0 (495.0) | 0.708 |
| pH | 7.28 (0.73) | 7.29 (0.61) | 7.28 (0.71) | 0.541 |
| Base excess | −8.0 (32.0) | −6.0 (25.0) | −9.0 (32.0) | 0.053 |
| Lactate (mg/dL) | 4.0 (23.4) | 3.4 (22.9) | 4.3 (18.5) | 0.114 |
| INR | 1.2 (14.7) | 1.2 (6.3) | 1.2 (14.7) | 0.355 |
| At conclusion of MTP | ||||
| Hg (g/dL) | 12.1 (12.2) | 13.4 (8.1) | 10.5 (8.1) | <0.001 |
| Platelets | 142.5 (373.0) | 140.0 (301.0) | 143.0 (373.0) | 0.484 |
| pH | 7.38 (0.37) | 7.38 (0.25) | 7.38 (0.37) | 0.850 |
| Base excess | −2.5 (27.0) | −2.0 (19.0) | −3.0 (27.0) | 0.561 |
| Lactate (mg/dL) | 2.7 (12.5) | 2.4 (7.7) | 3.0 (12.4) | 0.293 |
| INR | 1.3 (2.9) | 1.3 (2.2) | 1.4 (1.9) | 0.010 |
| 24 hours after conclusion of MTP | ||||
| Hg (g/dL) | 10.2 (9.5) | 11.9 (5.3) | 8.9 (4.0) | <0.001 |
| Platelets | 112.5 (301.0) | 122.0 (301.0) | 109.0 (272.0) | 0.040 |
| pH | 7.39 (0.42) | 7.38 (0.25) | 7.39 (0.42) | 0.559 |
| Base excess | −1.0 (18.0) | −1.0 (15.0) | −2.0 (15.0) | 0.623 |
| Lactate (mg/dL) | 1.7 (9.1) | 1.7 (9.0) | 1.7 (5.6) | 0.502 |
| INR | 1.4 (3.4) | 1,4 (1.4) | 1.5 (3.4) | 0.371 |
| At discharge | ||||
| Hg (mg/dL) | 9.5 (8.8) | 10.3 (8.8) | 8.9 (6.4) | <0.001 |
Variables are reported as medians (IQR).
P values were extracted from t-test or Mann-Whitney test.
Hg, hemoglobin; INR, international normalized ratio; MTP, massive transfusion protocol.