Comparison of baseline demographics and injury characteristics between overtransfused and non-overtransfused patients
| Total (n=140) | Overtransfused (n=61) | Non-overtransfused (n=79) | P value | |
| Age (y) | 39.0 (83.0) | 36.0 (66.0) | 46.0 (83.0) | 0.202 |
| Male | 74.3% (104/140) | 80.3% (49/61) | 69.6% (55/79) | 0.151 |
| Penetrating | 38.4% (53/138) | 52.5% (32/61) | 27.3% (21/77) | 0.003 |
| ED Shock Index | 0.9 (1.9) | 0.9 (1.9) | 0.9 (1.8) | 0.753 |
| >0.9 | 43.4% (59/136) | 46.7% (28/60) | 40.8% (31/76) | 0.492 |
| ED SBP (mm Hg) | 122.5 (157.0) | 119.0 (157.0) | 127.0 (147.0) | 0.541 |
| <90 | 19.9% (27/136) | 23.3% (14/60) | 17.1% (13/76) | 0.366 |
| ED GCS | 15.0 (12.0) | 14.5 (12.0) | 15.0 (12.0) | 0.293 |
| <9 | 24.3% (33/136) | 16.7% (10/60) | 30.3% (23/76) | 0.066 |
| ISS | 24.0 (58.0) | 18.5 (44.0) | 26.0 (58.0) | 0.035 |
| AIS head ≥3 | 35.0% (48/137) | 30.0% (18/60) | 39.0% (30/77) | 0.275 |
| AIS chest ≥3 | 46.7% (64/137) | 40.0% (24/60) | 51.9% (40/77) | 0.164 |
| AIS abdomen ≥3 | 31.4% (43/137) | 40.0% (24/60) | 24.7% (19/77) | 0.055 |
| AIS extremity ≥3 | 38.7% (53/137) | 23.3% (14/60) | 50.6% (39/77) | 0.001 |
| ED disposition | 0.677 | |||
| OR | 50.7% (71/140) | 52.5% (32/61) | 49.4% (39/79) | |
| IR | 3.6% (5/140) | 4.9% (3/61) | 2.5% (2/79) | |
| ICU | 45.0% (63/140) | 42.6% (26/61) | 46.8% (37/79) | |
| Other | 0.7% (1/140) | 0.0% (0/61) | 1.3% (1/79) | |
| Vasopressors prior to MTP delivery | 30.0% (42/140) | 27.9% (17/61) | 31.6% (25/79) | 0.629 |
| MTP delivery (min) | 10.0 (28.0) | 9.0 (18.0) | 10.0 (28.0) | 0.861 |
| MTP duration (hours) | 5.4 (23.0) | 5.3 (21.0) | 5.5 (23.0) | 0.271 |
| Vasopressors at conclusion of MTP | 21.4% (30/140) | 19.7% (12/61) | 22.8% (18/79) | 0.656 |
Categorical variables are reported as % (n) and continuous variables as medians (IQR).
P values were extracted from Χ2 or Fisher’s exact test for categorical variables, and from t-test or Mann-Whitney test for continuous variables.
AIS, Abbreviated Injury Scale; ED, emergency department; GCS, Glasgow Coma Scale; ICU, intensive care unit; IR, interventional radiology; ISS, Injury Severity Score; MTP, massive transfusion protocol; OR, operating room; SBP, systolic blood pressure.