Demographic and injury characteristics by admission fibrinogen levels
| Fibrinogen <150 mg/dL (n=20) | Fibrinogen 150 mg/dL to 200 mg/dL (n=76) | Fibrinogen >200 mg/dL (n=321) | P value | |
| Age, md (IQR) | 25 (21.5–32.5) | 30 (24.0–40.5) | 43 (27–55) | <0.001 |
| Blunt mechanism of injury, n (%) | 5 (25) | 45 (54.2) | 238 (74.1) | 0.03 |
| Land transport, n (%) | 8 (40) | 46.0 (60.5) | 189.0 (58.9) | 0.23 |
| Admission SI, mn (SD) | 1.2 (1.03) | 0.94 (0.46) | 0.73 (0.29) | <0.001 |
| Admission GCS, md (IQR) | 3 (2-7) | 14 (4–15) | 14 (7–15) | <0.001 |
| ISS, md (IQR) | 34 (25–41) | 27.0 (21.0–34.5) | 26 (19–30) | 0.001 |
| Lactate (mmol/L), md (IQR) | 6.1 (4.8–11.5) | 5.2 (3.6–8.6) | 3.5 (2.6–4.9) | <0.001 |
| Platelets (×1000 /µL), mn (SD) | 178.6 (54.3) | 223.2 (81.7) | 240.4 (68.2) | 0.003 |
| INR, md (IQR) | 1.8 (1.6–2.0) | 1.2 (1.1–1.4) | 1.1 (1.0–1.2) | 0.001 |
Demographics and injury characteristics by admission fibrinogen <150, 150–200, and >200.
GCS, Glasgow Coma Scale; INR, international normalized ratio; ISS, Injury Severity Score; md, median; mn, mean; n (%), frequency, percent; SI, Shock Index.