Clinical InvestigationDiabetes Mellitus and Risk of Venous Thromboembolism
Section snippets
Data Sources
The number of patients discharged from short-stay nonfederal hospitals throughout the United States with a diagnostic code for diabetes mellitus from 1979 to 2005 was obtained from the NHDS.14 Among these patients the number with pulmonary embolism, deep venous thrombosis, or the combination of pulmonary embolism and/or deep venous thrombosis (VTE) was determined. The NHDS consists of data obtained annually from approximately 270,000 sampled inpatient records from about 500 nonfederal
RESULTS
During the 27 years of study, among 92,240,000 patients discharged from short-stay hospitals from 1979 to 2005 with diabetes mellitus, VTE was diagnosed in 1,267,000 patients (1.4%) (Table 1). Among 699,858,000 patients who did not have diabetes mellitus, the incidence was similar, 1.3% (Table 1). The incidence of pulmonary embolism, deep venous thrombosis, and VTE in patients with diabetes mellitus increased to age 80 years just as it increased in patients who did not have diabetes mellitus (
DISCUSSION
Among all hospitalized patients, the incidence of VTE increased with age until 80 years. Patients with diabetes mellitus were not an exception to this; an age-related increased incidence of VTE in patients with diabetes mellitus was shown. However, the relative risk for VTE (comparing patients with diabetes mellitus to those who did not have diabetes mellitus) decreased with age until 70 years. In patients with uncomplicated diabetes mellitus who did not have stroke, heart failure, cancer, or
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