Trends in First Gabapentin and Pregabalin Prescriptions in Primary Care in the United Kingdom, 1993-2017

JAMA. 2018 Nov 27;320(20):2149-2151. doi: 10.1001/jama.2018.12358.

Abstract

This study examined the rates of patients in the United Kingdom treated with gabapentin and pregabalin for the first time, and the rates of these patients with an off-label indication or a coprescription of opioids or benzodiazepines.

MeSH terms

  • Analgesics / therapeutic use*
  • Analgesics, Opioid / therapeutic use
  • Anticonvulsants / therapeutic use
  • Drug Prescriptions / statistics & numerical data*
  • Drug Therapy, Combination / adverse effects
  • Drug Utilization / trends
  • Gabapentin / therapeutic use*
  • Humans
  • Off-Label Use / statistics & numerical data
  • Pregabalin / therapeutic use*
  • Primary Health Care
  • United Kingdom

Substances

  • Analgesics
  • Analgesics, Opioid
  • Anticonvulsants
  • Pregabalin
  • Gabapentin