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Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses.
Wu J, Vodovotz Y, Abdelhamid S, Guyette FX, Yaffe MB, Gruen DS, Cyr A, Okonkwo DO, Kar UK, Krishnamoorthi N, Voinchet RG, Billiar IM, Yazer MH, Namas RA, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Zuckerbraun BS, Johansson PI, Stensballe J, Morrissey JH, Tracy RP, Wisniewski SR, Neal MD, Sperry JL, Billiar TR; PAMPer study group. Wu J, et al. Among authors: billiar im. Cell Rep Med. 2021 Dec 21;2(12):100478. doi: 10.1016/j.xcrm.2021.100478. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028617 Free PMC article.
Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill.
Bonaroti J, Billiar I, Moheimani H, Wu J, Namas R, Li S, Kar UK, Vodovotz Y, Neal MD, Sperry JL, Billiar TR. Bonaroti J, et al. Among authors: billiar i. Front Immunol. 2022 Nov 30;13:1038086. doi: 10.3389/fimmu.2022.1038086. eCollection 2022. Front Immunol. 2022. PMID: 36532045 Free PMC article.