A battery of monoclonal antibodies (mAbs) against brain cell nuclei has been generated by
repeated immunizations. One of these, mAb A60, recognizes a vertebrate nervous …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor
neuron death. ALS can be induced by mutations in the superoxide dismutase 1 gene (SOD1)…

Teratogens, substances that may cause fetal abnormalities during development, are responsible
for a significant number of birth defects. Animal models used to predict teratogenicity …

Alpha-modified minimum essential medium (αMEM) has been found to cross-link a 1% gellan
gum solution, resulting in the formation of a self-supporting hydrogel in 1:1 and 5:1 ratios …

Background The diagnosis of autism spectrum disorder (ASD) at the earliest age possible is
important for initiating optimally effective intervention. In the United States the average age …

Calcium-alginate hydrogel has been widely studied as a material for cell encapsulation for
tissue engineering. At present, the effect that cells have on the degradation of alginate …

The use of biopolymers from different sources has been investigated for many years for
pharmaceutical and biomedical applications. This chapter provides a short overview on the …

Despite recent success, many fast-disintegrating tablets (FDTs) still face problems of low
mechanical strength, poor mouth-feel and higher disintegration times. This study aimed to …

A method for the production of complex cell-laden structures is reported, which allows high-levels
of spatial control over mechanical and chemical properties. The potential of this …

Since ancient times, drugs have been administered via the nasal route for therapeutic and
recreational purposes. The interest in, and importance, of the systemic effects of drugs …