The authors of the international bestseller Business Model Generation explain how to create
value propositions customers can’t resist Value Proposition Design helps you tackle the …

… The Cambridge project, under the direction of Alan Smith, drew on that department's
expertise, dating back to the work of Bullard, Everett and Smith (1965) and including earlier …

A short sequence of amino acids including Lys-128 is required for the normal nuclear
accumulation of wild-type and deleted forms of SV40 large T antigen. A cytoplasmic large T mutant …

A battery of monoclonal antibodies (mAbs) against brain cell nuclei has been generated by
repeated immunizations. One of these, mAb A60, recognizes a vertebrate nervous …

Specific aspects of cache memories that are investigated include: the cache fetch algorithm (demand
versus prefetch), the placement and replacement algorithms, line size, store-…

Background Lenvatinib in combination with pembrolizumab or everolimus has activity against
advanced renal cell carcinoma. The efficacy of these regimens as compared with that of …

We present a revised classification for extant ferns, with emphasis on ordinal and familial
ranks, and a synopsis of included genera. Our classification reflects recently published …

The gene associated with cystic fibrosis (CF) encodes a membrane-associated, N-linked
glycoprotein called CFTR. Mutations wem introduced into CFTR at residues known to be …

Background Standard therapy for advanced endometrial cancer after failure of platinum-based
chemotherapy remains unclear. Methods In this phase 3 trial, we randomly assigned, in a …

Cystic fibrosis is a regulated Cl-channel, for which structure-function relationships have
begun to be established, and insight into the functions of individual domains has come from …