[HTML][HTML] Clinical features and prognostic factors in Covid-19: a prospective cohort study

S de Bruin, LD Bos, MA van Roon, AM Tuip-de Boer… - …, 2021 - thelancet.com
Background Mortality rates are high among hospitalized patients with COVID-19, especially
in those intubated on the ICU. Insight in pathways associated with unfavourable outcome …

[HTML][HTML] Validation of volatile metabolites of pulmonary oxidative injury: a bench to bedside study

…, MR Smit, NFL Heijnen, AM Tuip-de Boer… - ERJ Open …, 2023 - Eur Respiratory Soc
Background Changes in exhaled volatile organic compounds (VOCs) can be used to
discriminate between respiratory diseases, and increased concentrations of hydrocarbons are …

[HTML][HTML] Cardiac arrest patients have an impaired immune response, which is not influenced by induced hypothermia

CJ Beurskens, J Horn, AMT de Boer, MJ Schultz… - Critical Care, 2014 - Springer
Introduction Induced hypothermia is increasingly applied as a therapeutic intervention in ICUs.
One of the underlying mechanisms of the beneficial effects of hypothermia is proposed to …

Kinetics of plasma biomarkers of inflammation and lung injury in surgical patients with or without postoperative pulmonary complications

…, TN Weingarten, AM Tuipde Boer… - European Journal of …, 2017 - journals.lww.com
BACKGROUND Postoperative pulmonary complications (PPCs) are common after major
abdominal surgery. The kinetics of plasma biomarkers could improve identification of patients …

[HTML][HTML] Plasma suPAR as a prognostic biological marker for ICU mortality in ARDS patients

DGPJ Geboers, FM de Beer, AMT Boer… - Intensive care …, 2015 - Springer
Purpose We investigated the prognostic value of plasma soluble urokinase plasminogen
activator receptor (suPAR) on day 1 in patients with the acute respiratory distress syndrome (…

Transfusion of 35-day stored RBCs in the presence of endotoxemia does not result in lung injury in humans

…, ME van Hezel, B Cortjens, AM Tuip-de Boer… - Critical care …, 2016 - journals.lww.com
Objective: Transfusion-related acute lung injury is the leading cause of transfusion-related
mortality. Preclinical studies have shown that aged RBCs can induce transfusion-related …

Aged versus fresh autologous platelet transfusion in a two‐hit healthy volunteer model of transfusion‐related acute lung injury

…, N van Mourik, EHT Lim, AM Tuipde Boer… - …, 2022 - Wiley Online Library
Background Transfusion‐related acute lung injury (TRALI) is a severe complication of blood
transfusion that is thought of as a two‐hit event: first the underlying patient condition (eg, …

[HTML][HTML] Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury

…, APJ Vlaar, NP Juffermans, AM Tuip-de Boer… - PloS one, 2012 - journals.plos.org
Introduction Uric acid released from injured tissue is considered a major endogenous
danger signal and local instillation of uric acid crystals induces acute lung inflammation via …

[HTML][HTML] Soluble urokinase-type plasminogen activator receptor levels in patients with burn injuries and inhalation trauma requiring mechanical ventilation: an …

Y Backes, KF van der Sluijs, AM Tuip de Boer… - Critical Care, 2011 - Springer
Introduction Soluble urokinase-type plasminogen activator receptor (suPAR) has been
proposed as a biologic marker of fibrinolysis and inflammation. The aim of this study was to …

[HTML][HTML] Transfusion of female blood in a rat model is associated with red blood cells entrapment in organs

A Alshalani, MB de Wissel, AM Tuip-de Boer… - Plos one, 2023 - journals.plos.org
Transfusion of red blood cells (RBCs) has been associated with adverse outcomes. Mechanisms
may be related to donor sex and biological age of RBC. This study hypothesized that …