Current treatment and recent progress in gastric cancer

SS Joshi, BD Badgwell - CA: a cancer journal for clinicians, 2021 - Wiley Online Library
Gastric cancer is not a top‐10 malignancy in the United States but represents one of the most
common causes of cancer death worldwide. Biological differences between tumors from …

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

…, S Zhang, D Hao, Y Lu, S Zhao, BD Badgwell… - Nature medicine, 2021 - nature.com
Intratumoral heterogeneity (ITH) is a fundamental property of cancer; however, the origins of
ITH remain poorly understood. We performed single-cell transcriptome profiling of …

[HTML][HTML] The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse

…, J Zimmerer, T Bakalakos, B Badgwell… - The Journal of …, 2003 - Am Soc Clin Investig
IFN-α activates the signal transducer and activator of transcription (STAT) family of proteins;
however, it is unknown whether IFN-α exerts its antitumor actions primarily through a direct …

Mammography before diagnosis among women age 80 years and older with breast cancer

BD Badgwell, SH Giordano, ZZ Duan… - Journal of Clinical …, 2008 - ascopubs.org
Purpose Screening mammography guidelines for patients age 80 years and older are variable.
We determined the effect of mammography use on stage at breast cancer diagnosis and …

Comprehensive geriatric assessment of risk factors associated with adverse outcomes and resource utilization in cancer patients undergoing abdominal surgery

B Badgwell, J Stanley, GJ Chang… - Journal of surgical …, 2013 - Wiley Online Library
Background The purpose of this prospective study was to identify risk factors for adverse
outcomes or increased resource utilization after abdominal cancer surgery in geriatric patients. …

Phase II trial of laparoscopic hyperthermic intraperitoneal chemoperfusion for peritoneal carcinomatosis or positive peritoneal cytology in patients with gastric …

B Badgwell, M Blum, P Das, J Estrella, X Wang… - Annals of surgical …, 2017 - Springer
Purpose The aim of this phase II study was to perform neoadjuvant hyperthermic intraperitoneal
chemoperfusion (HIPEC) via a minimally invasive approach without cytoreduction for …

Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response

R Wang, S Song, K Harada, FG Amlashi, B Badgwell… - Gut, 2020 - gut.bmj.com
Objective Peritoneal carcinomatosis (PC) occurs frequently in patients with gastric adenocarcinoma
(GAC) and confers a poor prognosis. Multiplex profiling of primary GACs has been …

Yield of staging laparoscopy and lavage cytology for radiologically occult peritoneal carcinomatosis of gastric cancer

…, K Fournier, P Mansfield, JA Ajani, BD Badgwell - Annals of surgical …, 2016 - Springer
Background This study aimed to identify the yield of staging laparoscopy with peritoneal
lavage cytology for gastric cancer patients and to track it over time. Methods The medical …

Does neoadjuvant treatment for gastric cancer patients with positive peritoneal cytology at staging laparoscopy improve survival?

B Badgwell, JN Cormier, S Krishnan, J Yao… - Annals of surgical …, 2008 - Springer
Background The purpose of this study was to identify clinicopathologic factors associated
with positive peritoneal cytology (PPC) in patients with gastric cancer and to compare the …

Palliation of malignant ascites

C Hodge, BD Badgwell - Journal of surgical oncology, 2019 - Wiley Online Library
Malignant ascites (MA) carries a poor prognosis. It can have a significant impact on quality
of life (QOL), with increasing abdominal distention, pain, and dyspnea. Diuretics typically do …