User profiles for Erin E Fox

Erin Elizabeth Fox, PhD

University of Texas Health Science Center at Houston
Verified email at uth.tmc.edu
Cited by 8753

Transfusion of plasma, platelets, and red blood cells in a 1: 1: 1 vs a 1: 1: 2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial

JB Holcomb, BC Tilley, S Baraniuk, EE Fox, CE Wade… - Jama, 2015 - jamanetwork.com
Importance Severely injured patients experiencing hemorrhagic shock often require massive
transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red …

The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks

JB Holcomb, DJ Del Junco, EE Fox, CE Wade… - JAMA …, 2013 - jamanetwork.com
Objective To relate in-hospital mortality to early transfusion of plasma and/or platelets and to
time-varying plasma:red blood cell (RBC) and platelet:RBC ratios. Design Prospective …

Damage control resuscitation in patients with severe traumatic hemorrhage: a practice management guideline from the Eastern Association for the Surgery of Trauma

…, JJ Como, BA Cotton, JJ Dubose, EE Fox… - Journal of Trauma …, 2017 - journals.lww.com
Background The resuscitation of severely injured bleeding patients has evolved into a multi-modal
strategy termed damage control resuscitation (DCR). This guideline evaluates …

Trends in 1029 trauma deaths at a level 1 trauma center: impact of a bleeding control bundle of care

BT Oyeniyi, EE Fox, M Scerbo, JS Tomasek, CE Wade… - Injury, 2017 - Elsevier
Background Over the last decade the age of trauma patients and injury mortality has increased.
At the same time, many centers have implemented multiple interventions focused on …

Clinical and mechanistic drivers of acute traumatic coagulopathy

…, HA Phelan, DJ Del Junco, EE Fox… - Journal of Trauma …, 2013 - journals.lww.com
BACKGROUND Acute traumatic coagulopathy (ATC) occurs after severe injury and shock
and is associated with increased bleeding, morbidity, and mortality. The effects of ATC and …

Parental age and risk of childhood cancer: a pooled analysis

KJ Johnson, SE Carozza, EJ Chow, EE Fox… - …, 2009 - journals.lww.com
Background: Few risk factors for childhood cancer are well-established. We investigated
whether advancing parental age increases childhood cancer risk. Methods: We assessed the …

Every minute counts: time to delivery of initial massive transfusion cooler and its impact on mortality

…, EE Fox, T O'Keeffe, K Inaba, E Bulger… - Journal of Trauma …, 2017 - journals.lww.com
BACKGROUND American College of Surgeons Trauma Quality Improvement Best Practices
recommends initial massive transfusion (MT) cooler delivery within 15 minutes of protocol …

Pragmatic randomized optimal platelet and plasma ratios (PROPPR) trial: design, rationale and implementation

S Baraniuk, BC Tilley, DJ Del Junco, EE Fox… - Injury, 2014 - Elsevier
Background Forty percent of in-hospital deaths among injured patients involve massive
truncal haemorrhage. These deaths may be prevented with rapid haemorrhage control and …

Resuscitate early with plasma and platelets or balance blood products gradually: findings from the PROMMTT study

DJ Del Junco, JB Holcomb, EE Fox… - Journal of Trauma …, 2013 - journals.lww.com
BACKGROUND The trauma transfusion literature has yet to resolve which is more important
for hemorrhaging patients, transfusing plasma and platelets along with red blood cells (…

Early and empirical high-dose cryoprecipitate for hemorrhage after traumatic injury: the CRYOSTAT-2 randomized clinical trial

R Davenport, N Curry, EE Fox, H Thomas, J Lucas… - Jama, 2023 - jamanetwork.com
Importance Critical bleeding is associated with a high mortality rate in patients with trauma.
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …