CYSTIC fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane Cl −
channel regulated by cyclic AMP-dependent phosphorylation and by intracellular ATP 1–7 . …

Adipose tissue depots originate from distinct precursor cells, are functionally diverse, and
modulate disease processes in a depot-specific manner. However, the functional properties of …

Complement receptor (CR)-mediated phagocytosis of Mycobacterium tuberculosis by
macrophages results in intracellular survival, suggesting that M. tuberculosis interferes with …

Atherosclerosis is increasingly recognized as a chronic inflammatory disease. Although a
variety of inflammatory markers (ie, C-reactive protein) have been associated with …

Pseudomonas aeruginosa, an opportunistic human pathogen, causes acute pneumonia in
patients with hospital-acquired infections and is commonly associated with chronic lung …

Cystic fibrosis is caused by mutations in the gene coding for the cystic fibrosis transmembrane
conductance regulator (CFTR). To further our understanding of CFTR's function and …

Production of pyocyanin enhances Pseudomonas aeruginosa virulence. Many of pyocyanin's
in vitro and in vivo cytotoxic effects on human cells appear to result from its ability to redox …

Statins, a group of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors,
are widely used in clinical practice for their efficacy in producing significant reductions in …

Rationale: Airway infection with Haemophilus influenzae causes airway inflammation, and
isolation of new strains of this bacteria is associated with increased risk of exacerbations in …

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance
regulator (CFTR), a membrane glycoprotein that forms Cl- channels. Previous work has …