Background To determine whether a restrictive strategy of red-cell transfusion and a liberal
strategy produced equivalent results in critically ill patients, we compared the rates of death …

… MD, FRCPC; Wells, George PhD; Marshall, John MD, FRCSC; Tweeddale, Martin MD,
PhD, FRCPC; Pagliarello, Giuseppe MD, FRCSC; Schweitzer, Irwin MSc The Transfusion …

In 4,470 critically ill patients, we examined the impact of transfusion practice on mortality
rates. As compared with survivors, patients who died in intensive care units (ICU) had lower …

Objective To compare a restrictive versus a liberal transfusion strategy in patients with
moderate to severe closed head injury following multiple trauma in 13 Canadian intensive care …

Background: To identify opportunities for quality improvement, the nutrition adequacy of
critically ill surgical patients, in contrast to medical patients, is described. Methods: International, …

… MD, MHSc(Epid), FRCPC; Wells, George PhD; Martin, Claudio MD, MSc, FRCPC;
Tweeddale, Martin MD, PhD, FRCPC; Marshall, John MD, FRCSC; Blajchman, Morris MD …

Objective. —To evaluate the effects of a restrictive and a liberal red blood cell (RBC)
transfusion strategy on mortality and morbidity in critically ill patients. Study Design. —Multicenter, …

Objectives: Accurate prognostic information in patients with severe traumatic brain injury
remains limited, but mortality following the withdrawal of life-sustaining therapies is high and …

Objectives To determine the degree of interinstitutional transfusion practice variation and
reasons why red cells are administered in critically ill patients. Study design Multicentre cohort …

Background The minimum duration of pulselessness required before organ donation after
circulatory determination of death has not been well studied. Methods We conducted a …