Assessment of risk of bias is regarded as an essential component of a systematic review on
the effects of an intervention. The most commonly used tool for randomised trials is the …

Non-randomised studies of the effects of interventions are critical to many areas of healthcare
evaluation, but their results may be biased. It is therefore important to understand and …

Objective: The purpose of this article was to evaluate the clinical and basic science evidence
surrounding the hypothesis that stretching improves performance. Data Sources and …

Background The objective of most biomedical research is to determine an unbiased estimate
of effect for an exposure on an outcome, ie to make causal inferences about the exposure. …

Background Our aim was to assess the strength of the controversial association between
thrombophilia and fetal loss, and to examine whether it varies according to the timing or …

Background: The reason some patients with deep venous thrombosis (DVT) develop the
postthrombotic syndrome is not well understood. Objective: To determine the frequency, time …

IN BRIEF: Stretching recommendations are clouded by misconceptions and conflicting research
reports. This review of the current literature on stretching and range-of-motion increases …

Since the early 1980s, stretching has been promoted as a method to prevent injury and
improve athletic performance. Although research suggests that this may be true for regular …

Background: Small bowel obstruction (SBO) is a major cause of morbidity and financial
expenditure in hospitals around the world. The leading cause of SBO in the western world has …

Many analyses of observational data are attempts to emulate a target trial. The emulation of
the target trial may fail when researchers deviate from simple principles that guide the …