Introduction Orthopedic trauma patients may have poor recall of their injuries and treatment.
This may lead to poor adherence to instructions. The purposes of this project were to …

Background At the initiation of the COVID-19 pandemic, restrictions forced researchers to
decide whether to continue their ongoing clinical trials. The PREPARE (Pragmatic …

Introduction Gunshot wounds to the brain (GSWB) confer high lethality and uncertain
recovery. It is unclear which patients benefit from aggressive resuscitation, and furthermore …

Methods: We reviewed a consecutive series of patients with intertrochanteric hip fractures
treated with a fixed angle device at 9 centers and compared corrected tip-apex distance and …

Introduction Pragmatic trials in comparative effectiveness research assess the effects of
different treatment, therapeutic, or healthcare options in clinical practice. They are characterized …

Methods: Randomized, double-blind, placebo-controlled trial of single dose reltecimod (0.5
mg/kg) administered within 6 hours of NSTI diagnosis at 65 of 93 study sites. Inclusion: …

… Leighton, MD Joanne Fraifogl, BS Heather A. Vallier, MD, FAAOS Paul Tornetta III, MD,
FAAOS Guillermo R. Pechero Orthopaedic Trauma Research Consortium …

Introduction: Pragmatic trials in comparative effectiveness research assess the effects of
different treatment, therapeutic, or healthcare options in clinical practice. They are characterized …

Background Preoperative antiseptic skin solutions are used prior to most surgical procedures;
however, there is no definitive research comparing infection-related outcomes following …

Objectives: Surgical site infections in orthopaedic trauma are a significant problem with
meaningful patient and health care system–level consequences. Direct application of antibiotics …