Background The successful treatment of intraabdominal infection requires a combination of
anatomical source control and antibiotics. The appropriate duration of antimicrobial therapy …

Efficient, nonselective methods to obtain DNA from the environment are needed for rapid
and thorough analysis of introduced microorganisms in environmental samples and for …

Severe sepsis, systemic inflammatory response syndrome (SIRS), and traumatic brain injury
are frequently associated with hyperglycemia in non-diabetic patients. In patients suffering …

Background A recent prospective, multicenter, randomized controlled trial found that 4 days
of antibiotics after source control of complicated intra-abdominal infections resulted in similar …

Oxidative stress exacerbates brain damage following ischemia-reperfusion and traumatic
brain injury (TBI). Management of TBI and critically ill patients commonly involves use of …

Historically, osteosarcoma has been a problematic metastatic disease, with 40–80% of
patients developing pulmonary metastasis after primary tumor resection. Recent treatment …

Background: Recent studies have suggested the length of treatment of intra-abdominal
infections (IAIs) can be shortened without detrimental effects on patient outcomes. However, data …

PURPOSE: The current management of osteosarcoma (OS) entails an aggressive preoperative
and postoperative chemotherapeutic regimen with limb salvage surgery. Despite these …

Background: Sepsis accounts for 10% of intensive care unit admissions and significant
healthcare costs. Although the mortality rate from sepsis has been decreasing with better critical …

Objectives The onset of the national stay-at-home orders accompanied by a surge in firearm
sales has elevated the concerns of clinicians and public health authorities. The purpose of …