Oxidation of cysteine pairs to disulfide requires cellular factors present in the bacterial
periplasmic space. DsbB is an E. coli membrane protein that oxidizes DsbA, a periplasmic dithiol …

Importance Severely injured patients experiencing hemorrhagic shock often require massive
transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red …

Cysteine hydropersulfide (CysSSH) occurs in abundant quantities in various organisms, yet
little is known about its biosynthesis and physiological functions. Extensive persulfide …

Background: With the evolution of multi-slice helical computed tomographic angiography (MCTA),
the optimal imaging modality for arterial injury in the traumatized lower extremity has …

Genetic variation is associated with outcome disparity in critical illness. We sought to determine
if race is independently associated with the development of posttraumatic sepsis and …

… Kenji Inaba: I think just to get to that point right away, before I forget, that is absolutely true
and I think that both the DNR status, as well as the focus of the injuries, definitely will impact …

METHODS The American Association for the Surgery of Trauma Aortic Occlusion for
Resuscitation in Trauma and Acute Care Surgery registry prospectively identified trauma patients …

Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in the emergency departments worldwide. The …

Background The resuscitation of severely injured bleeding patients has evolved into a multi-modal
strategy termed damage control resuscitation (DCR). This guideline evaluates …

Background Adhesive small bowel obstruction (ASBO) is a common surgical emergency,
causing high morbidity and even some mortality. The adhesions causing such bowel …