Following a year of valganciclovir prophylaxis, a lung transplant recipient developed
cytomegalovirus (CMV) infection that became resistant to ganciclovir, as confirmed by detection of …

Increasing bacterial resistance and poor patient adherence rates limit the effectiveness of
conventional antibiotic therapies for urinary tract infection (UTI). The objective of this study was …

Objectives: Preliminary data suggest that antibiotic discontinuation in patients with negative
quantitative bronchoscopy and symptom resolution will not increase mortality. Because our …

Since the first New Delhi metallo-beta-lactamase (NDM) report in 2009, NDM has spread
globally causing various types of infections. NDM-positive organisms produce in vitro …

Complicated intra-abdominal infections (cIAI) represent a large proportion of all hospital
admissions and are a major cause of morbidity and mortality in the intensive care unit. Rising …

The widespread emergence of antibiotic‐resistant gram‐negative organisms has compromised
the utility of current treatment options for severe infections caused by these pathogens. …

Background: Urinary tract infections (UTI) are among the most common bacterial diseases
worldwide, with significant clinical and economic burden. Surveillance of pathogen …

Guidelines for the treatment of sepsis, febrile neutropenia, and hospital-acquired pneumonia
caused by Pseudomonas aeruginosa include empirical regimens incorporating two …

Bacterial vaginosis (BV) is a complex vaginal infection most commonly associated with
women of child-bearing age. Risk factors for BV are numerous. There are currently multiple …

Vancomycin is a glycopeptide antibiotic that was isolated in 1956 from the actinomycete
Streptomyces orientalis. It consists of a seven-membered peptide chain and two sugar moieties, …