… Michael M. Tiller, MD … Pusateri, Cardin, and Tiller are military service members or
federal/contracted employees of the US government. This work was prepared as part of …

Objectives Prehospital transfusion can be life-saving when transport is delayed but
conventional plasma, red cells, and whole blood are often unavailable out of hospital. Shelf-stable …

A general framework is presented for the optimal design of nonlinear parabolic systems which
govern a variety of processes including solidification. In this paper, the spatial domain is …

Introduction: Traumatic shock and hemorrhage (TSH) is a leading cause of preventable death
in military and civilian populations. Using a TSH model, we compared plasma with whole …

Introduction We present the experience of our US Navy Role 2’s deployment to the US Central
Command area of responsibility in support of Operation Inherent Resolve and serving a …

BACKGROUND Uncontrolled hemorrhage is the leading cause of potentially survivable
combat casualty mortality, with 86.5% of cases resulting from noncompressible torso …

Background: Decompensated hemorrhagic shock (DHS) is the leading cause of preventable
death in combat casualties.“Golden hour” resuscitation effects on cerebral blood flow and …

Introduction Hemorrhage is the leading cause of preventable death, with a majority of mortalities
in the prehospital setting. Current hemorrhage resuscitation guidelines cannot predict …

Background Although hemorrhage remains the leading cause of survivable death in
casualties, modern conflicts are becoming more austere limiting available resources to include …

In this paper we present an approach to integrating optimisation tools with simulation
software to achieve user-defined objectives. A formal protocol is presented, including specific …