Operative fixation of rib fractures after blunt trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma

…, N Patel, MB Patel, L Alarcon, PL Bosarge… - Journal of Trauma …, 2017 - journals.lww.com
BACKGROUND Rib fractures are identified in 10% of all injury victims and are associated
with significant morbidity (33%) and mortality (12%). Significant progress has been made in …

Effect of out-of-hospital tranexamic acid vs placebo on 6-month functional neurologic outcomes in patients with moderate or severe traumatic brain injury

…, J Christenson, LJ Morrison, RJ Frascone, PL Bosarge… - Jama, 2020 - jamanetwork.com
Importance Traumatic brain injury (TBI) is the leading cause of death and disability due to
trauma. Early administration of tranexamic acid may benefit patients with TBI. Objective To …

Stress-induced hyperglycemia is associated with higher mortality in severe traumatic brain injury

PL Bosarge, TH Shoultz, RL Griffin… - Journal of trauma and …, 2015 - journals.lww.com
BACKGROUND An association between stress-induced hyperglycemia (SIH) and increased
mortality has been demonstrated following trauma. Experimental animal model data …

Early initiation of extracorporeal membrane oxygenation improves survival in adult trauma patients with severe adult respiratory distress syndrome

PL Bosarge, LA Raff, G McGwin Jr… - Journal of Trauma …, 2016 - journals.lww.com
Background The use of extracorporeal membrane oxygenation (ECMO) in the trauma population
has been reported to have a mortality benefit in patients with severe refractory hypoxic …

Evaluation and management of traumatic diaphragmatic injuries: A Practice Management Guideline from the Eastern Association for the Surgery of Trauma

…, BRH Robinson, L Alarcon, PL Bosarge… - Journal of Trauma …, 2018 - journals.lww.com
… MD; Robinson, Bryce RH MD; Alarcon, Louis MD; Bosarge, Patrick L. MD; Dorion, Heath
MD; Haut, Elliott R. MD, PhD; Juern, Jeremy MD; Madbak, Firas MD; Reddy, Srinivas MD; …

Novel oral anticoagulants and trauma: the results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial

L Kobayashi, G Barmparas, P Bosarge… - Journal of Trauma …, 2017 - journals.lww.com
BACKGROUND The number of anticoagulated trauma patients is increasing. Trauma
patients on warfarin have been found to have poor outcomes, particularly after intracranial …

Management of penetrating extraperitoneal rectal injuries: An Eastern Association for the Surgery of Trauma practice management guideline

PL Bosarge, JJ Como, N Fox, Y Falck-Ytter… - Journal of Trauma …, 2016 - journals.lww.com
BACKGROUND The management of penetrating rectal trauma invokes a complex decision
tree that advocates the principles of proximal diversion (diversion) of the fecal stream, …

Acute brain trauma, lung injury, and pneumonia: more than just altered mental status and decreased airway protection

…, JF Pittet, JD Kerby, PL Bosarge… - American Journal of …, 2017 - journals.physiology.org
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Even when
patients survive the initial insult, there is significant morbidity and mortality secondary to …

Outcomes after concomitant traumatic brain injury and hemorrhagic shock: a secondary analysis from the Pragmatic, Randomized Optimal Platelets and Plasma …

…, SN Appana, S Baraniuk, PL Bosarge… - Journal of trauma and …, 2017 - journals.lww.com
BACKGROUND Often the clinician is faced with a diagnostic and therapeutic dilemma in
patients with concomitant traumatic brain injury (TBI) and hemorrhagic shock (HS), as rapid …

Elevated syndecan-1 after trauma and risk of sepsis: a secondary analysis of patients from the pragmatic, randomized optimal platelet and plasma ratios (PROPPR) …

…, S Knoll, JD Kerby, JF Pittet, PL Bosarge… - Journal of the American …, 2018 - Elsevier
Background Endotheliopathy of trauma is characterized by breakdown of the endothelial
glycocalyx. Elevated biomarkers of endotheliopathy, such as serum syndecan-1 (Synd-1) ≥ 40 …