User profiles for Priya S Prakash
Priya PrakashUniversity of Chicago Verified email at surgery.bsd.uchicago.edu Cited by 1985 |
Interleukin-7 ameliorates immune dysfunction and improves survival in a 2-hit model of fungal sepsis
…, J McDonough, M Morre, PS Prakash… - The Journal of …, 2012 - academic.oup.com
Background. Secondary hospital-acquired fungal infections are common in critically-ill patients
and mortality remains high despite antimicrobial therapy. Interleukin-7 (IL-7) is a potent …
and mortality remains high despite antimicrobial therapy. Interleukin-7 (IL-7) is a potent …
Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through γδ T-cell IL-17 production in a murine model of sepsis
KR Kasten, PS Prakash, J Unsinger… - Infection and …, 2010 - Am Soc Microbiol
The sepsis syndrome represents an improper immune response to infection and is associated
with unacceptably high rates of mortality and morbidity. The interactions between T cells …
with unacceptably high rates of mortality and morbidity. The interactions between T cells …
Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation
Background Transfusion of stored blood is associated with increased complications.
Microparticles (MPs) are small vesicles released from RBCs that can induce cellular dysfunction, …
Microparticles (MPs) are small vesicles released from RBCs that can induce cellular dysfunction, …
Human microparticles generated during sepsis in patients with critical illness are neutrophil-derived and modulate the immune response
PS Prakash, CC Caldwell, AB Lentsch… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND Microparticles (MPs) are 0.3 μm to 1.0 μm vesicles generated after cell
activation or apoptosis that may play a role in the pathophysiology of sepsis. We sought to …
activation or apoptosis that may play a role in the pathophysiology of sepsis. We sought to …
Predictors of retained hemothorax in trauma: Results of an Eastern Association for the Surgery of Trauma multi-institutional trial
PS Prakash, SA Moore, JB Rezende-Neto… - Journal of Trauma …, 2020 - journals.lww.com
BACKGROUND The natural history of traumatic hemothorax (HTX) remains unclear. We
aimed to describe outcomes of HTX following tube thoracostomy drainage and to delineate …
aimed to describe outcomes of HTX following tube thoracostomy drainage and to delineate …
Similar hematological and biochemical parameters among periodontitis and control group subjects
S Prakash, K Dhingra, S Priya - European journal of dentistry, 2012 - thieme-connect.com
Objectives: There are conflicting reports in the past literature documenting the tendency of
anemia in patients with periodontitis. Hence, this study was undertaken to assess whether …
anemia in patients with periodontitis. Hence, this study was undertaken to assess whether …
[HTML][HTML] Neutrophil derived microparticles increase mortality and the counter-inflammatory response in a murine model of sepsis
BL Johnson III, EF Midura, PS Prakash, TC Rice… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Although advances in medical care have significantly improved sepsis survival, sepsis
remains the leading cause of death in the ICU. This is likely due to a lack of complete …
remains the leading cause of death in the ICU. This is likely due to a lack of complete …
Mechanisms underlying mouse TNF-α stimulated neutrophil derived microparticle generation
BL Johnson III, HS Goetzman, PS Prakash… - Biochemical and …, 2013 - Elsevier
Despite advances in understanding and treatment of sepsis, it remains a disease with high
mortality. Neutrophil Derived Microparticles (NDMPs) are present during sepsis and can …
mortality. Neutrophil Derived Microparticles (NDMPs) are present during sepsis and can …
Predictors of initial management failure in traumatic hemothorax: A prospective multicenter cohort analysis
…, MJ Seamon, JW Cannon, I Afif, PS Prakash, S Trpcic… - Surgery, 2023 - Elsevier
Background Traumatic hemothorax is common, and management failure leads to worse
outcomes. We sought to determine predictive factors and understand the role of trauma center …
outcomes. We sought to determine predictive factors and understand the role of trauma center …
Impact of caspase-8 and PKA in regulating neutrophil-derived microparticle generation
EF Midura, PS Prakash, BL Johnson III, TC Rice… - Biochemical and …, 2016 - Elsevier
The morbidity and mortality from sepsis continues to remain high despite extensive research
into understanding this complex immunologic process. Further, while source control and …
into understanding this complex immunologic process. Further, while source control and …