User profiles for Sheila M Keating

Sheila Keating

Vice President of Immunology at GigaGen, Inc.(Grifols); Associate Adjunct Professor UCSF; …
Verified email at gigagen.com
Cited by 7882

[HTML][HTML] Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans

H McShane, AA Pathan, CR Sander, SM Keating… - Nature medicine, 2004 - nature.com
Protective immunity against Mycobacterium tuberculosis depends on the generation of a T H
1-type cellular immune response, characterized by the secretion of interferon-γ (IFN-γ) from …

Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation

…, G Sciaranghella, MP Busch, SM Keating… - The Journal of …, 2013 - academic.oup.com
Background. The long-term impact of allogeneic hematopoietic stem cell transplantation (HSCT)
on human immunodeficiency virus type 1 (HIV-1) reservoirs in patients receiving …

The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women

SM Keating, ET Golub, M Nowicki, M Young, K Anastos… - Aids, 2011 - journals.lww.com
Objective: HIV causes inflammation that can be at least partially corrected by HAART. To
determine the qualitative and quantitative nature of cytokine perturbation, we compared …

[HTML][HTML] Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository

R Kassanjee, CD Pilcher, SM Keating, SN Facente… - Aids, 2014 - journals.lww.com
Objective: Cross-sectional HIV incidence surveillance, using assays that distinguish ‘recent’from
‘nonrecent’infections, has been hampered by inadequate performance and …

Viral load criteria and threshold optimization to improve HIV incidence assay characteristics

…, MP Busch, G Murphy, SN Facente, SM Keating… - Aids, 2016 - journals.lww.com
Objective: Assays for classifying HIV infections as ‘recent’or ‘nonrecent’for incidence
surveillance fail to simultaneously achieve large mean durations of ‘recent’infection (MDRIs) and …

Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with …

SM Keating, P Bejon, T Berthoud, JM Vuola… - The Journal of …, 2005 - journals.aai.org
Immunological memory is a required component of protective antimalarial responses raised
by T cell-inducing vaccines. The magnitude of ex vivo IFN-γ T cell responses is widely used …

Synergistic DNA–MVA prime-boost vaccination regimes for malaria and tuberculosis

…, AA Pathan, SJ McConkey, JM Vuola, SM Keating… - Vaccine, 2006 - Elsevier
T-cell-mediated responses against the liver-stage of Plasmodium falciparum are critical for
protection in the human irradiated sporozoite model and several animal models. …

[HTML][HTML] Compartmentalization of cerebrospinal fluid inflammation across the spectrum of untreated HIV-1 infection, central nervous system injury and viral …

M Gisslen, SM Keating, S Spudich, V Arechiga… - PLoS …, 2021 - journals.plos.org
Objective To characterize the evolution of central nervous system (CNS) inflammation in HIV-1
infection applying a panel of cerebrospinal fluid (CSF) inflammatory biomarkers to …

A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS, S/AS02A and MVA-CS

…, M Walther, JM Vuola, DP Webster, SM Keating… - Vaccine, 2006 - Elsevier
Heterologous prime-boost immunisation with RTS,S/AS02A and the poxvirus MVA-CS was
evaluated in 18 healthy malaria-naïve subjects in Oxford. Both priming with RTS,S and …

[HTML][HTML] Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of …

…, R Fromentin, AT Haase, D Hampton, SM Keating… - PLoS …, 2017 - journals.plos.org
Background Notwithstanding 1 documented case of HIV-1 cure following allogeneic stem
cell transplantation (allo-SCT), several subsequent cases of allo-SCT in HIV-1 positive …