[HTML][HTML] A review of pathophysiology, clinical features, and management options of COVID-19 associated coagulopathy

J Goswami, TA MacArthur, M Sridharan, RK Pruthi… - Shock, 2021 - journals.lww.com
There is increasing evidence that novel coronavirus disease 2019 (COVID-19) leads to a
significant coagulopathy, a phenomenon termed “COVID-19 associated coagulopathy.” COVID-…

DNase-mediated dissolution of neutrophil extracellular traps accelerates in vitro thrombin generation kinetics in trauma patients

J Goswami, TA MacArthur, C Mahony… - Shock, 2022 - journals.lww.com
Introduction: Neutrophil extracellular traps (NETs) trigger thrombin generation. We aimed to
characterize the effects of deoxyribonuclease (DNAse) on NET components (cell-free DNA […

Crystalloid volume is associated with short-term morbidity in children with severe traumatic brain injury: An Eastern Association for the Surgery of Trauma multicenter …

TA MacArthur, AM Vogel, AE Glasgow… - Journal of Trauma …, 2023 - journals.lww.com
OBJECTIVE This study examined differences in clinical and resuscitation characteristics
between injured children with and without severe traumatic brain injury (sTBI) and aimed to …

[HTML][HTML] Association of common medications and the risk of early-onset gastric cancer: a population-based matched study

TA MacArthur, WS Harmsen, J Mandrekar… - Journal of Cancer …, 2021 - hindawi.com
Background. Early-onset gastric cancer (EOGC, years at diagnosis) now comprises >30% of
new gastric cancers in the United States. It is hypothesized that chronic acid suppression …

Plasma thrombin generation kinetics vary by injury pattern and resuscitation characteristics in pediatric and young adult trauma patients

TA MacArthur, J Goswami, AS Howick… - Journal of trauma and …, 2023 - journals.lww.com
BACKGROUND Thrombin generation kinetics are not well studied in children. This study
aimed to assess how thrombin generation kinetics vary in pediatric and young adult (YA) …

Estradiol and dihydrotestosterone levels in COVID-19 patients

TA MacArthur, J Goswami, D Ramachandran… - Mayo Clinic …, 2023 - Elsevier
Objective To determine differences in plasma sex hormone levels in male and female coronavirus
disease 2019 (COVID-19) patients and healthy volunteers (HVs) because cell entry of …

Quantification of von Willebrand factor and ADAMTS-13 after traumatic injury: a pilot study

TA MacArthur, J Goswami, LM Tasson… - Trauma Surgery & …, 2021 - tsaco.bmj.com
Background Von Willebrand factor (VWF) is an acute phase reactant synthesized in the
megakaryocytes and endothelial cells. VWF forms ultra-large multimers (ULVWF) which are …

Interhospital variability in localization techniques for small pulmonary nodules in children: A pediatric surgical oncology research collaborative study

…, DR Lal, BS Rich, RD Glick, TA MacArthur… - Journal of pediatric …, 2022 - Elsevier
Background Pulmonary nodules that are deep within lung parenchyma and/or small in size
can be challenging to localize for biopsy. This study describes current trends in performance …

[HTML][HTML] Pediatric manifestations of Lynch Syndrome: a single center experience

TA MacArthur, LJ Ongie, BC Lanpher… - Journal of pediatric …, 2022 - Elsevier
Lynch syndrome is an autosomal dominant condition caused by a heterozygous variation in
one of the DNA mismatch repair (MMR) genes that pre-disposes individuals to early onset …

Thrombin generation kinetics are predictive of rapid transfusion in trauma patients meeting critical administration threshold

TA MacArthur, GM Spears, RA Kozar, J Dong, M Auton… - Shock, 2021 - journals.lww.com
Methods: In a prospective cohort study, trauma patients were enrolled over a 4.5-year period
and serial blood samples collected at various time points. We retrospectively stratified pts …